Volume 13, Issue 10 | October 2003

ARTICLES
- - An Evolutionary Analysis of Orphan Genes in Drosophila
    Tomislav Domazet-Loso
    Diethard Tautz
    First Published October 2, 2003
  - Extensive Exon Reshuffling Over Evolutionary Time Coupled to Trans-Splicing in Drosophila
    Mariano Labrador
    Victor G. Corces
    First Published October 2, 2003
LETTERS
- - Gene Loss, Protein Sequence Divergence, Gene Dispensability, Expression Level, and Interactivity Are Correlated in Eukaryotic Evolution
    Dmitri M. Krylov
    Yuri I. Wolf
    Igor B. Rogozin
    Eugene V. Koonin
    First Published October 2, 2003
  - Mystery of Intron Gain
    Alexei Fedorov
    Scott Roy
    Larisa Fedorova
    Walter Gilbert
    First Published January 1, 2003
  - Two Distinct Modes of Microsatellite Mutation Processes: Evidence From the Complete Genomic Sequences of Nine Species
    Daniel Dieringer
    Christian Schlötterer
    First Published October 2, 2003
  - Adaptive Evolution of MRG, a Neuron-Specific Gene Family Implicated in Nociception
    Sun Shim Choi
    Bruce T. Lahn
    First Published October 2, 2003
  - The Signature of Selection Mediated by Expression on Human Genes
    Araxi O. Urrutia
    Laurence D. Hurst
    First Published January 1, 2003
  - The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment
    Hilary F. Clark
    Austin L. Gurney
    Evangeline Abaya
    Kevin Baker
    Daryl Baldwin
    Jennifer Brush Jian Chen Bernard Chow Clarissa Chui Craig Crowley Bridget Currell Bethanne Deuel Patrick Dowd Dan Eaton Jessica Foster Christopher Grimaldi Qimin Gu Philip E. Hass Sherry Heldens Arthur Huang Hok Seon Kim Laura Klimowski Yisheng Jin Stephanie Johnson James Lee Lhney Lewis Dongzhou Liao Melanie Mark Edward Robbie Celina Sanchez Jill Schoenfeld Somasekar Seshagiri Laura Simmons Jennifer Singh Victoria Smith Jeremy Stinson Alicia Vagts Richard Vandlen Colin Watanabe David Wieand Kathryn Woods Ming-Hong Xie Daniel Yansura Sothy Yi Guoying Yu Jean Yuan Min Zhang
    ...[+42 authors]...,
    Zemin Zhang
    Audrey Goddard
    William I. Wood
    Paul Godowski
    First Published January 1, 2003
  - Single Nucleotide Variation Analysis in 65 Candidate Genes for CNS Disorders in a Representative Sample of the European Population
    Yun Freudenberg-Hua
    Jan Freudenberg
    Nadine Kluck
    Sven Cichon
    Peter Propping
    First Published October 2, 2003
  - Ethnic India: A Genomic View, With Special Reference to Peopling and Structure
    Analabha Basu
    Namita Mukherjee
    Sangita Roy
    Sanghamitra Sengupta
    Sanat Banerjee
    Madan Chakraborty Badal Dey Monami Roy
    ...[+3 authors]...,
    Bidyut Roy
    Nitai P. Bhattacharyya
    Susanta Roychoudhury
    Partha P. Majumder
    First Published October 2, 2003
  - Representational Oligonucleotide Microarray Analysis: A High-Resolution Method to Detect Genome Copy Number Variation
    Robert Lucito
    John Healy
    Joan Alexander
    Andrew Reiner
    Diane Esposito
    Maoyen Chi Linda Rodgers Amy Brady Jonathan Sebat Jennifer Troge Joseph A. West Seth Rostan Ken C.Q. Nguyen Scott Powers Kenneth Q. Ye
    ...[+10 authors]...,
    Adam Olshen
    Ennapadam Venkatraman
    Larry Norton
    Michael Wigler
    First Published January 1, 2003
Methods
- - Annotating Large Genomes With Exact Word Matches
    John Healy
    Elizabeth E. Thomas
    Jacob T. Schwartz
    Michael Wigler
    First Published January 1, 2003
  - DNA Enrichment by Allele-Specific Hybridization (DEASH): A Novel Method for Haplotyping and for Detecting Low-Frequency Base Substitutional Variants and Recombinant DNA Molecules
    Alec J. Jeffreys
    Celia A. May
    First Published October 2, 2003
  - Adenoviral Vectors Expressing siRNAs for Discovery and Validation of Gene Function
    Gert-Jan Arts
    Ellen Langemeijer
    Rudi Tissingh
    Libin Ma
    Heidi Pavliska
    Kristina Dokic Richele Dooijes Emir Mešić Remko Clasen Frits Michiels Jan van der Schueren Mark Lambrecht Sofie Herman Reginald Brys
    ...[+9 authors]...,
    Kim Thys
    Marcel Hoffmann
    Peter Tomme
    Helmuth van Es
    First Published January 1, 2003
  - High-Throughput Selection of Effective RNAi Probes for Gene Silencing
    Rajeev Kumar
    Douglas S. Conklin
    Vivek Mittal
    First Published October 2, 2003
  - RNAi Microarray Analysis in Cultured Mammalian Cells
    Spyro Mousses
    Natasha J. Caplen
    Robert Cornelison
    Don Weaver
    Mark Basik
    Sampsa Hautaniemi Abdel G. Elkahloun Roberto A. Lotufo
    ...[+3 authors]...,
    Ashish Choudary
    Edward R. Dougherty
    Ed Suh
    Olli Kallioniemi
    First Published October 2, 2003
  - Microfabricated Fountain Pens for High-Density DNA Arrays
    Matthew O. Reese
    R. Michae van Dam
    Axel Scherer
    Stephen R. Quake
    First Published January 1, 2003
  - Comprehensive Analysis of Orthologous Protein Domains Using the HOPS Database
    Christian E.V. Storm
    Erik L.L. Sonnhammer
    First Published October 2, 2003
RESOURCE
- - Development of Human Protein Reference Database as an Initial Platform for Approaching Systems Biology in Humans
    Suraj Peri
    J. Daniel Navarro
    Ramars Amanchy
    Troels Z. Kristiansen
    Chandra Kiran Jonnalagadda
    Vineeth Surendranath Vidya Niranjan Babylakshmi Muthusamy T.K.B. Gandhi Mads Gronborg Nieves Ibarrola Nandan Deshpande K. Shanker H.N. Shivashankar B.P. Rashmi M.A. Ramya Zhixing Zhao K.N. Chandrika N. Padma H.C. Harsha A.J. Yatish M.P. Kavitha Minal Menezes Dipanwita Roy Choudhury Shubha Suresh Neelanjana Ghosh R. Saravana Sreenath Chandran Subhalakshmi Krishna Mary Joy Sanjeev K. Anand V. Madavan Ansamma Joseph Guang W. Wong William P. Schiemann Stefan N. Constantinescu Lily Huang Roya Khosravi-Far Hanno Steen Muneesh Tewari Saghi Ghaffari Gerard C. Blobe Chi V. Dang Joe G.N. Garcia Jonathan Pevsner Ole N. Jensen Peter Roepstorff Krishna S. Deshpande
    ...[+43 authors]...,
    Arul M. Chinnaiyan
    Ada Hamosh
    Aravinda Chakravarti
    Akhilesh Pandey
    First Published October 2, 2003

Table of Contents

Volume 13, Issue 10 | October 2003

ARTICLES

An Evolutionary Analysis of Orphan Genes in Drosophila

Extensive Exon Reshuffling Over Evolutionary Time Coupled to Trans-Splicing in Drosophila

LETTERS

Gene Loss, Protein Sequence Divergence, Gene Dispensability, Expression Level, and Interactivity Are Correlated in Eukaryotic Evolution

Mystery of Intron Gain

Two Distinct Modes of Microsatellite Mutation Processes: Evidence From the Complete Genomic Sequences of Nine Species

Adaptive Evolution of MRG, a Neuron-Specific Gene Family Implicated in Nociception

The Signature of Selection Mediated by Expression on Human Genes

The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment

Single Nucleotide Variation Analysis in 65 Candidate Genes for CNS Disorders in a Representative Sample of the European Population

Ethnic India: A Genomic View, With Special Reference to Peopling and Structure

Representational Oligonucleotide Microarray Analysis: A High-Resolution Method to Detect Genome Copy Number Variation

Methods

Annotating Large Genomes With Exact Word Matches

DNA Enrichment by Allele-Specific Hybridization (DEASH): A Novel Method for Haplotyping and for Detecting Low-Frequency Base Substitutional Variants and Recombinant DNA Molecules

Adenoviral Vectors Expressing siRNAs for Discovery and Validation of Gene Function

High-Throughput Selection of Effective RNAi Probes for Gene Silencing

RNAi Microarray Analysis in Cultured Mammalian Cells

Microfabricated Fountain Pens for High-Density DNA Arrays

Comprehensive Analysis of Orthologous Protein Domains Using the HOPS Database

RESOURCE

Development of Human Protein Reference Database as an Initial Platform for Approaching Systems Biology in Humans

Table of Contents

Volume 13, Issue 10 | October 2003

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