Lymphopenia in the BB Rat Model of Type 1 Diabetes is Due to a Mutation in a Novel Immune-Associated Nucleotide (Ian)-Related Gene

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Figure 2.
Figure 2.

Sequence of the BB rat Immune Associated Nucleotide (Ian5) gene. A representative sequencing trace of DNA from BBDP/WorAp compared with wild-type BBDR/WorAp and F344 rats. The frameshift mutation at nucleotide position 478 in the DP rat DNA is indicated. DNA sequences were determined on an ABI PRISM 3700 DNA Analyzer (Applied Biosystems) and analyzed by the use of Phred, Phrap,Consed, and PolyPhred for sequence assembly and identification of sequence variants.

This Article

  1. Genome Res. 12: 1029-1039

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