Analyses of the Extent of Shared Synteny and Conserved Gene Orders between the Genome of Fugu rubripes and Human 20q

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Figure 5.
Figure 5.

Fugu/human 20q11.2–12 comparative gene map. This ideogram provides a more detailed comparison between the two Fugucontigs and a 7-Mb section of human 20q (a section that contains the human orthologs of two of the genes, KRML and TOP1, known to be duplicated in Fugu). The orthologs of ∼25% of the genes mapping to this region are represented on one or another of the twoFugu contigs. The distribution of the genes between the twoFugu contigs, however, appears to be random, indicating a pattern of duplication in the Fugu lineage followed by the loss (in the majority of cases) of one of the additional gene copies.

This Article

  1. Published in Advance April 12, 2002, doi: 10.1101/gr.221802 Genome Res. 12: 776-784

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