Table 1.
Distribution of the Different Genotypes at the ThreeEcl-loci in 91 Circling and 47 Noncircling Mice
| No. of risk alleles | Ecla (chrom 3) | Eclb (chrom 4) | Eclc (chrom 13) | No. of circling mice (% animals) | No. of noncircling mice (% animals) |
| 6 | AA | BB | CC | 11 (12) | 1 (2) |
| 5 | Aa | BB | CC | 14 (15) | 1 (2) |
| AA | BB | Cc | 12 (13) | 1 (2) | |
| AA | Bb | CC | 7 (7) | 2 (4) | |
| 4 | Aa | Bb | CC | 11 (12) | 2 (4) |
| Aa | BB | Cc | 10 (10) | 2 (4) | |
| AA | Bb | Cc | 4 (4) | 0 (0) | |
| AA | BB | cc | 3 (3) | 2 (4) | |
| aa | BB | CC | 3 (3) | 1 (2) | |
| AA | bb | CC | 0 (0) | 0 (0) | |
| 3 | aa | Bb | CC | 4 (4) | 2 (4) |
| aa | BB | Cc | 3 (3) | 1 (2) | |
| Aa | Bb | Cc | 3 (3) | 4 (8.5) | |
| AA | Bb | cc | 2 (2) | 4 (8.5) | |
| Aa | BB | cc | 1 (1) | 4 (8.5) | |
| AA | bb | Cc | 0 (0) | 4 (8.5) | |
| Aa | bb | Cc | 0 (0) | 0 (0) | |
| 2 | AA | bb | cc | 1 (1) | 1 (2) |
| Aa | Bb | cc | 1 (1) | 0 (0) | |
| aa | BB | cc | 1 (1) | 3 (6) | |
| aa | Bb | Cc | 0 (0) | 4 (8.5) | |
| Aa | bb | Cc | 0 (0) | 3 (6) | |
| aa | bb | CC | 0 (0) | 1 (2) | |
| 1 | Aa | bb | cc | 0 (0) | 3 (6) |
| aa | Bb | cc | 0 (0) | 1 (2) | |
| aa | bb | Cc | 0 (0) | 0 (0) | |
| 0 | aa | bb | cc | 0 (0) | 0 (0) |
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The noncircling mice represent a selected group that shows homozygosity for the recessive Ecs-gene. Upper cases represent risk-alleles derived from C57L/J and lower cases represent nonrisk alleles derived from SWR/J.
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↵This is the single circling mouse that did not inherit a copy of the Eclb-risk allele for the neighboring marker. A recombination between the marker and the risk conferring mutation may have occurred in this animal.
