Table 1.
Intracellular Localization and Antiviral Spectrum for Selected Mx Proteins
| Gene | Accession no. | Size (aa) | Intracellular localization | Antiviral specificity | |||||
| Virus | Family | ||||||||
| MxA | P20591 | 661 | Cytoplasm | Influenza virus, Thogoto virus | Orthomyxoviridae 1 | ||||
| Vesicular stomatitis virus | Rhabdoviridae 2 | ||||||||
| Measles virus | Paramyxoviridae 3 | ||||||||
| Hantaan virus | Bunyaviridae 4 | ||||||||
| Coxsackievirus B4 | Picornaviridae 5 | ||||||||
| Semliki Forest virus | Togaviridae 6 | ||||||||
| MxB | P20592 | 715 | Nucleus and cytoplasm | Inactive | |||||
| Mx1 | P09922 | 631 | Nucleus | Influenza virus, Thogoto virus, Dhori virus | Orthomyxoviridae 1 | ||||
| Mx2 | NP_38634 | 655 | Cytoplasm | Vesicular stomatitis virus | Rhabdoviridae 2 | ||||
| Hantann virus | Bunyaviridae 4 | ||||||||
| Mx1 | P18588 | 652 | Nucleus | Influenza virus, Thogoto virus | Orthomyxoviridae 1 | ||||
| Mx2 | P18589 | 659 | Cytoplasm | Vesicular stomatitis virus | Rhabdoviridae 2 | ||||
| LaCrosse virus, Rift Valley fever virus | Bunyaviridae 4 | ||||||||
| Mx3 | P18590 | 659 | Cytoplasm | Inactive | |||||
| Mx | Q92597 | 705 | Cytoplasm | Influenza virus | Orthomyxoviridae 1 | ||||
| Vesicular stomatitis virus | Rhabdoviridae 2 | ||||||||
| Mx | P33238 | 721 | Nucleus and cytoplasm | Inactive | |||||
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ped, negative-sense segmented RNA virus
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ped, negative-sense non-segmented RNA virus
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positive-sense non-segmented RNA virus
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ped, positive-sense, non-segmented RNA virus
