Identification of Multiple Genetic Loci Linked to the Propensity for “Behavioral Despair” in Mice

Table 3.

Significant Marker Pairs from Genome-Wide Interaction Analysis

Trait Marker 1 (genotype) Marker 2 (genotype) Lod score F-value % variance Significance level (α)
Tail suspension test D11Mit271 (B6/B6) DXMit172(B6/B6) 5.9 27.8 4.7 0.01
D6Mit183 (B6/B6) D11Mit271 (B6/B6) 5.0 21.0 3.6 0.05
  • Threshold lod scores (F-values) for significance levels of α = 0.05 and 0.01 are 4.14 (20.6) and 5.09 (23.9), respectively, by permutation analysis.

This Article

  1. Genome Res. 12: 357-366

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