Figure 4.
(A) Overlay of the super family of 57 metallochaperone homolog structures; three colors are used according to sequence classification of Fig. 1: Atx1-like (green), CopZ-like (blue), and MerP-like (red). The copper ion is shown as a green or a blue sphere for Atx1-like and CopZ-like structures, respectively; for MerP-like structures the mercury ion is shown in red. (B) Overlay of the super family of 116 structures, each corresponding to one soluble domain of a metal-transporting ATPase; two colors are used to distinguish between eukaryotes (green) and prokaryotes, including archaea (blue). The copper ion is shown as a sphere.
