Positional Candidate Cloning of a QTL in Dairy Cattle: Identification of a Missense Mutation in the Bovine DGAT1 Gene with Major Effect on Milk Yield and Composition

(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)

Click on image to view larger version.

Figure 5.
Figure 5.

Lod score due to LD when including (blue) or excluding (red) the fourDGAT1 polymorphisms in a combined linkage and LD multipoint maximum likelihood mapping method (Farnir et al. 2002). The lod score corresponds to the log10 of the ratio between the likelihood of the data assuming linkage and LD between the markers and the QTL and the likelihood of the data assuming linkage in the absence of LD. The positions of the microsatellites and SNP markers used in the analysis are shown on the x-axis, and the position of theDGAT1 SNPs is marked by a red arrow at the top of the figure.

This Article

  1. Genome Res. 12: 222-231

Preprint Server