Changes in Gene Expression Profiles in Developing B Cells of Murine Bone Marrow

Table 3D.

Genes Distinguishing Immature from Mature Cells

affy_id Description Function PRE LAR SMA IMM MAT Cluster p(H)
J04170_s_at Mouse B-cell differentiation antigen Lyb-2.1 protein, complete cds.(=CD72) intercell communic 1015 1929 2856 5057 1906 13 0.00076
X12616_s_at Mouse c-fes proto-oncogene mRNA for c-fes protein. Signaling 252 77 26 399 167 13 0.00555
I11330_s_at Mus musculus protein tyrosine phosphatase (PAC-1) mRNA, complete cds. Signaling 674 484 1090 2079 790 13 0.00213
ET62844_f_at Mus musculus immunoglobulin-like receptor PIRA6 (12M1) mRNA, complete cds. intercell communic 147 111 154 263 257 14 0.00472
u96689_s_at Mus musculus immunoglobulin-like receptor PIRB1 (7M5) mRNA, complete cds. intercell communic 112 269 245 542 557 14 0.00949
x04648_s_at Mouse mRNA for IgG1/IgG2b Fc receptor (FcR). intercell communic 202 504 868 1877 1865 14 0.00012
j05479_s_at Mouse calcineurin catalytic subunit mRNA, complete cds. Signaling 457 522 682 1039 1046 14 0.00048
U68171_s_at Mus musculus cyclic nucleotide phosphodiesterase PDE7A2 (MMPDE7A) mRNA, complete cds. Signaling 144 286 304 491 426 14 0.00328
L02241_s_at Mouse protein kinase inhibitor (testicular isoform) mRNA, complete cds.(=inhibitor of cAMP dependent protein kinase) Signaling 154 18 92 376 248 14 0.00264
u57325_s_at Mus musculus PS-2short mRNA, complete cds. Apoptosis 357 211 950 1000 785 15 0.00087
U35623_s_at Mus musculus EAT/MCL-1 mRNA, complete cds. Apoptosis 1272 1132 2801 6862 4182 14 0.00008
U88908_s_at Mus musculus inhibitor of apoptosis protein 1 mRNA, complete cds. Apoptosis 229 301 1611 1578 2217 15 0.00016
u78031_s_at Mus musculus apoptosis inhibitor bcl-x) gene, exon 3 and complete cds. Apoptosis 530 999 1793 444 152 10 0.00027
Msa.463.0_at Mouse bcl-2 gene encoding mbcl-2-beta Apoptosis 122 −38 −8 154 511 17 0.00028
L16956_at Mouse protein-tyrosine kinase (Jak2) mRNA, complete cds. Signaling 198 225 228 157 502 17 0.01466
L16956_at Mouse protein-tryosine kinase (Jak2) mRNA, complete cds. Signaling 198 225 228 157 502 17 0.01466
L16956_g_at Mouse protein-tryosine kinase (Jak2) mRNA, complete cds. Signaling 47 73 105 21 505 17 0.00615
u51907_s_at Mus musculus TRAF family member associated NF-kappa B activator (TANK) mRNA, complete cds. Signaling 93 103 273 247 444 17 0.00013
U12919_s_at Mus musculus adenylyl cyclase type VII mRNA, complete cds. Signaling 187 113 316 315 587 17 0.01204
D13759_s_at Mouse mRNA for proto-oncogene protein.(=MAPKKK8) Signaling −37 57 −44 26 143 17 0.0056
x83932_s_at M. musculus mRNA for ryanodine receptor type 1. Signaling −11 11 −1 96 342 17 0.00128
j05265_s_at Mouse interferon gamma receptor mRNA, complete cds. intercell communic 661 521 644 542 1178 17 0.01011
U53696_s_at Mus musculus class II cytokine receptor 4 (CRF2–4) mRNA, complete cds.(=IL-10 receptor) intercell communic 182 163 218 293 693 17 0.00115
L31580_s_at Mouse G protein-coupled receptor (EBI 1) mRNA, complete cds.(+CCR7) intercell communic 178 280 606 529 1330 17 0.00024
Msa.549.0_s_at Murine complement receptor type 2 (CR2) mRNA, complete cds intercell communic −10 −10 29 98 581 17 0.00145
X71788_s_at M. musculus bir-1 gene for Burkitt lymphoma receptor 1 homologue. (=CXCR5) intercell communic −29 −56 −40 276 1076 17 0.00037
m18184_s_at Mouse lymphocyte differentiation antigen (Ly-6.2) mRNA, complete cds. (=TAP) intercell communic 689 63 119 1857 10119 17 0.00006
m34163_s_at Mouse low affinity IgE receptor (Fc-epsilon-RII) mRNA, complete cds. intercell communic −13 3 50 1471 6536 17 0.00037
  • Genes distinguishing immature from mature cells with potential implications for positive/negative selection and response to B-cell receptor crosslinking (apoptosis vs. proliferation).

This Article

  1. Genome Res. 12: 98-111

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