Shedding of Lipoproteins and Autolysins by Bacillus subtilis Δlgt
| Proteins | Function/Similarity | 168 | ΔIgt |
| Metabolism of the cell wall | |||
| LytDW | N-acetylglucosaminidase (major autolysin) | + | +++ |
| PbpClipo | penicillin-binding protein 3 | − | +++ |
| YodJlipo | D-alanyl-D-alanine carboxypeptidase | − | +++ |
| YvcEW | cell wall-binding protein | + | +++ |
| Transport/binding proteins and lipoproteins | |||
| FeuAlipo | iron-uptake system (binding protein) | − | +++ |
| FhuDlipo | ferrichrome ABC transporter (binding protein) | − | ++ |
| MntAlipo | manganese ABC transporter (binding protein) | + | +++ |
| MsmElipo | multiple sugar ABC transporter (binding protein) | − | ++ |
| OppAlipo | oligopeptide ABC transporter (binding protein) | + | +++ |
| OpuAClipo pst | glycine betaine ABC transporter (binding protein) | − | +++ |
| PstSlipo pst | phosphate ABC transporter (binding protein) | ++ | +++ |
| RbsBlipo | ribose ABC transporter (binding protein) | − | +++ |
| YcdHlipo pst | zinc ABC transporter (binding protein) | + | +++ |
| YclQlipo | ferrichrome ABC transporter (binding protein) | +++ | +++ |
| YdhFRR lipo pst | similar to unknown proteins from B. subtilis | + | ++ |
| YfiYlipo | iron(III) dicitrate ABC transporter (binding protein) | − | +++ |
| YfmClipo | ferrichrome ABC transporter (binding protein) | + | +++ |
| YqiXlipo pst | amino acid ABC transporter (binding protein) | + | +++ |
| YrpElipo pst | similar to unknown proteins from B. subtilis | − | +++ |
| YusAlipo | probably part of the S box regulon | − | +++ |
| YxeBlipo | ferrichrome ABC transporter (binding protein) | − | +++ |
| Information pathways RNA synthesis/regulation | |||
| YwtF | transcriptional regulator (similar tolytR) | + | +++ |
| Phage-related functions | |||
| XepA | PBSX prophage lytic exoenzyme | + | +++ |
| XlyA | N-acetylmuramoyl-L-alanine amidase | + | +++ |
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The absence of proteins from the extracellular proteome of the parental strain 168 is indicated with −, and their presence with +, ++, or +++ if the protein is present at low, average, or high levels, respectively. Proteins present at elevated levels in the medium of theΔIgt strain are indicated with ++ or +++. Proteins that are induced upon phosphate starvation are indicated withpst. Proteins with a twin-arginine motif in the signal peptide are marked RR. Lipoproteins are indicated withlipo. Extracellular proteins containing typical wall-binding repeats in the mature part are marked with W.
