A Proteomic View on Genome-Based Signal Peptide Predictions

Table 3.

Extracellular Proteome Changes in the Absence of SPase II

Proteins ΔlspA
Metabolism of carbohydrates
AmyE −−
Csn
Metabolism of proteins
Epr
WprARR +
Metabolism of lipids
LipARR
Metabolism of phosphate
GlpQpst
Metabolism of the cell wall
LytDW
Transport/binding proteins
MntAlipo +
YxeBlipo +
Detoxification
PenP
Phage-related functions
XepA
XkdK
XkdM
XlyAW
Similar to unknown proteins
YncM
YolA −−
YrpD
YwoF
YxaK
YxkC
  • +, Proteins present at elevated levels on the extracellular proteome of the ΔlspA strain. −, Proteins present at reduced levels. −−, Proteins that are no longer detected on the extracellular proteome of the ΔlspA strain. pst, Proteins that are induced upon phosphate starvation. RR, Proteins with a twin-arginine motif in the signal peptide.lipo, Lipoproteins. W, Extracellular proteins containing wall-binding repeats in the mature part of the proteins.

This Article

  1. Genome Res. 11: 1484-1502

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