Microsatellites in the Eukaryotic DNA Mismatch Repair Genes as Modulators of Evolutionary Mutation Rate

Table 1.

Microsatellites in the Coding Regions of the DNA MMR Genes

MSH2 MSH3 MSH6 MLH1 PMS2 MLH3
Homo sapiens A7 A8, A7 C8, A7, T7 none A8 A9, A8
Mus musculus none none T7 none none
Saccharomyces cerevisiae none A10, A7 A8, T7, T7 T7, T7 A8, A7 none
Saccharomyces pombe A7, A7 A7 T8, A7, T7 A7, A7 A7
Drosophila melanogaster none A7 A7
Arabidopsis thaliana A7 none none none
MutS MutL
Escherichia coli none none
  • In yeast, PMS1.

  • AAGAAAAAA in place of human A8 homologous sequence.

  • (–) No available data.

  • Swi4 gene, which has homology to MSH3.

This Article

  1. Genome Res. 11: 1145-1146

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