Sequence-Based Design of Single-Copy Genomic DNA Probes for Fluorescence In Situ Hybridization

Table 2.

Distributions of Single Copy Sequence Intervals

Chromosome Interval length 21q 22q
>1bp ≥2kb ≥2.3kb >1bp ≥2kb ≥2.3kb
Number of intervals 27189 1459 1046 57536 1931 1506
Mean length (kb) 0.55 3.02 3.37 0.58 3.44 3.81
Kurtosis 82.6 109.7 105.4 71.8 18.4 17.1
Range of inter-interval distances (kb) 0.022–15.3 2.05–274 2.35–304 0.009–20.6 2.09–205 2.39–344
Average distance between intervals (kb) 1.13 20.9 29.2 0.58 17.4 22.3
  • Defined as the distance between the start coordinates of adjacent intervals.

This Article

  1. Genome Res. 11: 1086-1094

Preprint Server