Sequence-Based Design of Single-Copy Genomic DNA Probes for Fluorescence In Situ Hybridization

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Figure 5.Figure 5.
Figure 5.

Probability of detecting single-copy segments within genomic domains of varying lengths. Probabilities for single-copy segments of ≥1, ≥2, ≥3, and ≥4 kb are plotted as indicated; (A) chromosome 21q, (B) chromosome 22q. Overlapping genomic intervals were analyzed in increments of 5 kb up to 218 kb; however, only interval lengths up to 130 kb are indicated for chromasome 22.

This Article

  1. Genome Res. 11: 1086-1094

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