Volume 11, Issue 5 | May 2001

EDITORIAL
- - Unlimited Access—Limitless Success
    Laurie Goodman
    First Published May 1, 2001
COMMENTARIES
- - Contemplating the End of the Beginning
    Francis S. Collins
    First Published May 1, 2001
  - The Human Genome Sequence Expedition: Views from the “Base Camp”
    Eric D. Green
    Aravinda Chakravarti
    First Published May 1, 2001
  - Segmental Duplications: What's Missing, Misassigned, and Misassembled—and Should We Care?
    Evan E. Eichler
    First Published May 1, 2001
  - Through the Lens of the Sequence
    Ellen Wright Clayton
    First Published May 1, 2001
INSIGHT/OUTLOOK
- - Are We Polyploids? A Brief History of One Hypothesis
    Wojciech Makałowski
    First Published May 1, 2001
  - Complete DNA Sequence of Lactococcus lactis Adds Flavor to Genomics
    Oscar P. Kuipers
    First Published May 1, 2001
REPORT
- - Identification and Characterization of the Potential Promoter Regions of 1031 Kinds of Human Genes
    Yutaka Suzuki
    Tatsuhiko Tsunoda
    Jun Sese
    Hirotoshi Taira
    Junko Mizushima-Sugano
    Hiroko Hata Toshio Ota Takao Isogai Toshihiro Tanaka Yusuke Nakamura Akira Suyama
    ...[+6 authors]...,
    Yoshiyuki Sakaki
    Shinichi Morishita
    Kousaku Okubo
    Sumio Sugano
    First Published April 11, 2001
ARTICLES
- - The Complete Human Olfactory Subgenome
    Gustavo Glusman
    Itai Yanai
    Irit Rubin
    Doron Lancet
    First Published May 1, 2001
  - Whole Proteome pI Values Correlate with Subcellular Localizations of Proteins for Organisms within the Three Domains of Life
    Russell Schwartz
    Claire S. Ting
    Jonathan King
    First Published April 11, 2001
LETTERS
- - From First Base: The Sequence of the Tip of the X Chromosome of Drosophila melanogaster, a Comparison of Two Sequencing Strategies
    Panayiotis V. Benos
    Melanie K. Gatt
    Lee Murphy
    David Harris
    Bart Barrell
    Concepcion Ferraz Sophie Vidal Christine Brun Jacques Demaille Edouard Cadieu Stephane Dreano Stéphanie Gloux Valerie Lelaure Stephanie Mottier Francis Galibert Dana Borkova Belen Miñana Fotis C. Kafatos Slava Bolshakov Inga Sidén-Kiamos George Papagiannakis Lefteris Spanos Christos Louis Encarnación Madueño Beatriz de Pablos Juan Modolell Annette Peter Petra Schöttler Meike Werner Fotini Mourkioti Nicole Beinert Gordon Dowe Ulrich Schäfer Herbert Jäckle Alain Bucheton Debbie Callister Lorna Campbell Nadine S. Henderson Paul J. McMillan Cathy Salles Evelyn Tait Phillipe Valenti Robert D.C. Saunders
    ...[+38 authors]...,
    Alain Billaud
    Lior Pachter
    David M. Glover
    Michael Ashburner
    First Published May 1, 2001
  - The Complete Genome Sequence of the Lactic Acid Bacterium Lactococcus lactis ssp. lactis IL1403
    Alexander Bolotin
    Patrick Wincker
    Stéphane Mauger
    Olivier Jaillon
    Karine Malarme
    First Published April 11, 2001
  - The Basic Helix-Loop-Helix Protein Family: Comparative Genomics and Phylogenetic Analysis
    Valérie Ledent
    Michel Vervoort
    First Published May 1, 2001
  - Ancient Genome Duplications Did Not Structure the Human Hox-Bearing Chromosomes
    Austin L. Hughes
    Jack da Silva
    Robert Friedman
    First Published April 11, 2001
  - Euteleost Fish Genomes are Characterized by Expansion of Gene Families
    Marc Robinson-Rechavi
    Oriane Marchand
    Héctor Escriva
    Pierre-Luc Bardet
    Dominique Zelus
    First Published May 1, 2001
  - Genomic Anatomy of a Premier Major Histocompatibility Complex Paralogous Region on Chromosome 1q21–q22
    Takashi Shiina
    Asako Ando
    Yumiko Suto
    Fumio Kasai
    Atsuko Shigenari
    Nobusada Takishima Eri Kikkawa Kyoko Iwata Yuko Kuwano Yuka Kitamura Yumiko Matsuzawa Kazumi Sano Masahiro Nogami Hisako Kawata Suyun Li Yasuhito Fukuzumi Masaaki Yamazaki Hiroyuki Tashiro Gen Tamiya Atsushi Kohda Katsuzumi Okumura Toshimichi Ikemura Eiichi Soeda
    ...[+18 authors]...,
    Nobuhisa Mizuki
    Minoru Kimura
    Seiamak Bahram
    Hidetoshi Inoko
    First Published May 1, 2001
  - Computational Inference of Homologous Gene Structures in the Human Genome
    Ru-Fang Yeh
    Lee P. Lim
    Christopher B. Burge
    First Published May 1, 2001
  - Evaluation of Gene-Finding Programs on Mammalian Sequences
    Sanja Rogic
    Alan K. Mackworth
    Francis B.F. Ouellette
    First Published May 1, 2001
  - Characterization of the Genomic Xist Locus in Rodents Reveals Conservation of Overall Gene Structure and Tandem Repeats but Rapid Evolution of Unique Sequence
    Tatyana B. Nesterova
    Sergey Ya. Slobodyanyuk
    Eugene A. Elisaphenko
    Alexander I. Shevchenko
    Colette Johnston
    Marina E. Pavlova
    ...[+1 authors]...,
    Igor B. Rogozin
    Nikolay N. Kolesnikov
    Neil Brockdorff
    Suren M. Zakian
    First Published May 1, 2001
  - Human–Ovine Comparative Sequencing of a 250-kb Imprinted Domain Encompassing the Callipyge (clpg) Locus and Identification of Six Imprinted Transcripts: DLK1, DAT, GTL2, PEG11, antiPEG11, and MEG8
    Carole Charlier
    Karin Segers
    Danny Wagenaar
    Latifa Karim
    Stéphane Berghmans
    Olivier Jaillon Tracy Shay
    ...[+2 authors]...,
    Jean Weissenbach
    Noelle Cockett
    Gabor Gyapay
    Michel Georges
    First Published May 1, 2001
METHODS
- - Predicting Deleterious Amino Acid Substitutions
    Pauline C. Ng
    Steven Henikoff
    First Published May 1, 2001
  - Basecalling with LifeTrace
    Dirk Walther
    Gábor Bartha
    Macdonald Morris
    First Published May 1, 2001
  - Gene Structure Prediction and Alternative Splicing Analysis Using Genomically Aligned ESTs
    Zhengyan Kan
    Eric C. Rouchka
    Warren R. Gish
    David J. States
    First Published May 1, 2001
  - Directed Gap Closure in Large-Scale Sequencing Projects
    Marcus Frohme
    Anamaria A. Camargo
    Claudia Czink
    Adriana Y. Matsukuma
    Andrew J.G. Simpson
    First Published May 1, 2001
RESOURCE
- - Assembly, Annotation, and Integration of UNIGENE Clusters into the Human Genome Draft
    Degen Zhuo
    Wei D. Zhao
    Fred A. Wright
    Hee-Yung Yang
    Jian-Ping Wang
    Russell Sears Troy Baer Do-Hun Kwon David Gordon Solomon Gibbs Dean Dai Qing Yang Joe Spitzner
    ...[+8 authors]...,
    Ralf Krahe
    Don Stredney
    Al Stutz
    Bo Yuan
    First Published April 11, 2001
ERRATUM
- - Errata for vol. 11, p. 531
    First Published May 1, 2001

Table of Contents

Volume 11, Issue 5 | May 2001

EDITORIAL

Unlimited Access—Limitless Success

COMMENTARIES

Contemplating the End of the Beginning

The Human Genome Sequence Expedition: Views from the “Base Camp”

Segmental Duplications: What's Missing, Misassigned, and Misassembled—and Should We Care?

Through the Lens of the Sequence

INSIGHT/OUTLOOK

Are We Polyploids? A Brief History of One Hypothesis

Complete DNA Sequence of Lactococcus lactis Adds Flavor to Genomics

REPORT

Identification and Characterization of the Potential Promoter Regions of 1031 Kinds of Human Genes

ARTICLES

The Complete Human Olfactory Subgenome

Whole Proteome pI Values Correlate with Subcellular Localizations of Proteins for Organisms within the Three Domains of Life

LETTERS

From First Base: The Sequence of the Tip of the X Chromosome of Drosophila melanogaster, a Comparison of Two Sequencing Strategies

The Complete Genome Sequence of the Lactic Acid Bacterium Lactococcus lactis ssp. lactis IL1403

The Basic Helix-Loop-Helix Protein Family: Comparative Genomics and Phylogenetic Analysis

Ancient Genome Duplications Did Not Structure the Human Hox-Bearing Chromosomes

Euteleost Fish Genomes are Characterized by Expansion of Gene Families

Genomic Anatomy of a Premier Major Histocompatibility Complex Paralogous Region on Chromosome 1q21–q22

Computational Inference of Homologous Gene Structures in the Human Genome

Evaluation of Gene-Finding Programs on Mammalian Sequences

Characterization of the Genomic Xist Locus in Rodents Reveals Conservation of Overall Gene Structure and Tandem Repeats but Rapid Evolution of Unique Sequence

Human–Ovine Comparative Sequencing of a 250-kb Imprinted Domain Encompassing the Callipyge (clpg) Locus and Identification of Six Imprinted Transcripts: DLK1, DAT, GTL2, PEG11, antiPEG11, and MEG8

METHODS

Predicting Deleterious Amino Acid Substitutions

Basecalling with LifeTrace

Gene Structure Prediction and Alternative Splicing Analysis Using Genomically Aligned ESTs

Directed Gap Closure in Large-Scale Sequencing Projects

RESOURCE

Assembly, Annotation, and Integration of UNIGENE Clusters into the Human Genome Draft

ERRATUM

Errata for vol. 11, p. 531

Table of Contents

Volume 11, Issue 5 | May 2001

Share this issue

EDITORIAL

COMMENTARIES

INSIGHT/OUTLOOK

REPORT

ARTICLES

LETTERS

METHODS

RESOURCE

ERRATUM