First Pass Annotation of Promoters on Human Chromosome 22

Table 4.

Correlation of CpG Islands Filtered by Predicted Promoter Regions with Gene Annotation on Human Chromosome 22

CpG Islands correlated with PromoterInspector regions 358 (100%)
Gene group # abs. rel. O
All genes 545 170 47.5% 6.8
Known genes 247 105 29.5% 11.5
Related genes 150 29 8.1% 5.4
Predicted genes 148 41 11.4% 3.7
Pseudo genes 134 2 0.5% 0.4
Additional predictions 186 51.8%
  • (#) Number of annotated genes.

  • (abs) Absolute number of predicted promoter regions that were found near annotated genes.

  • (rel) Percentage of predicted promoter regions that were found near annotated genes.

  • (O) X-fold overrepresentation, i.e., number of predicted promoter predictions that were found near annotated genes divided by the number that would be expected to be located near these genes if the same number of positions were distributed randomly across the chromosome.

  • Due to a small number of double scoring regions (a region is scored twice if it is supported by genes from different gene groups), the total number of annotation supported regions is not equal to the sum over the number of gene group-related annotation-supported promoter regions.

This Article

  1. Genome Res. 11: 333-340

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