Composite rearrangements. Symbols are the same as in Fig. 1. The shading of the arrows corresponds to the shading of the centromeres. (A) Nonsyntenic gene couples SuYER157w-SuYMR090w andSuYMR091c-SuYLR039c. (ΔSuYMR091c) The absence of hybridization of the corresponding probe onto chromosomeSuXIII. (B) Nonsyntenic gene couples SuYLL055w-SuYEL071w and SuYLL057c-SuYMR053c. TheS. uvarum ORFs homologous with S. cerevisiae subtelomeric genes lie in hatched areas that represent, by analogy with S. cerevisiae, the subtelomeric regions in S. uvarum. Similarly, the contiguous ovals symbolize S. uvarum telomeres.SuYLL056c and SuYLL057c are not represented in a hatched area on chromosome SuXIII because they were associated to SuYMR053c whose ortholog in S. cerevisiae is not localized in the subtelomeric regions. (C) Nonsyntenic gene couples SuYJL217w-SuYPL273w and SuYJL217w-SuYFL053w. Same representation for subtelomeres and telomeres as in (B). (Curved arrow) Inversion of the orientation of SuYFL053w.
