Volume 10, Issue 8 | August 2000

INSIGHT/OUTLOOK
- - A Chimpanzee Genome Project Is a Biomedical Imperative
    Ajit Varki
    First Published August 1, 2000
  - WABA Success: A Tool for Sequence Comparison between Large Genomes
    David L. Baillie
    Ann M. Rose
    First Published August 1, 2000
  - Guilt by Association: Contextual Information in Genome Analysis
    L. Aravind
    First Published August 1, 2000
REVIEW
- - Automation for Genomics, Part One: Preparation for Sequencing
    Deirdre Meldrum
    First Published August 1, 2000
REPORTS
- - Genomic Sequence Analysis of the Mouse Naip Gene Array
    Matthew G. Endrizzi
    Vey Hadinoto
    Joseph D. Growney
    Webb Miller
    William F. Dietrich
    First Published August 1, 2000
  - Gene Survey of the Pathogenic Protozoan Trypanosoma cruzi
    Betina M. Porcel
    Anh-Nhi Tran
    Martti Tammi
    Zoltan Nyarady
    Maria Rydåker
    Turan P. Urmenyi
    ...[+1 authors]...,
    Edson Rondinelli
    Ulf Pettersson
    Bj̈orn Andersson
    Lena Åslund
    First Published August 1, 2000
  - GT Repeats Are Associated with Recombination on Human Chromosome 22
    Jacek Majewski
    Jurg Ott
    First Published August 1, 2000
ARTICLES
- - Conservation, Regulation, Synteny, and Introns in a Large-scale C. briggsae–C. elegans Genomic Alignment
    W. James Kent
    Alan M. Zahler
    First Published August 1, 2000
  - Genome-wide Detection of Allelic Imbalance Using Human SNPs and High-density DNA Arrays
    Rui Mei
    Patricia C. Galipeau
    Cynthia Prass
    Anthony Berno
    Ghassan Ghandour
    Nila Patil
    ...[+1 authors]...,
    Roger K. Wolff
    Mark S. Chee
    Brian J. Reid
    David J. Lockhart
    First Published August 1, 2000
LETTERS
- - Discovery of a Novel, Paternally Expressed Ubiquitin-specific Processing Protease Gene through Comparative Analysis of an Imprinted Region of Mouse Chromosome 7 and Human Chromosome 19q13.4
    Joomyeong Kim
    Vladimir N. Noskov
    Xiaochen Lu
    Anne Bergmann
    Xiaojia Ren
    Tiffany Warth
    Paul Richardson
    Natalya Kouprina
    Lisa Stubbs
    First Published August 1, 2000
  - Alfresco—A Workbench for Comparative Genomic Sequence Analysis
    Niclas Jareborg
    Richard Durbin
    First Published August 1, 2000
  - High-resolution Genetic and Physical Map of the Lgn1 Interval in C57BL/6J Implicates Naip2 or Naip5 in Legionella pneumophila Pathogenesis
    Joseph D. Growney
    William F. Dietrich
    First Published August 1, 2000
  - Eukaryote-specific Domains in Translation Initiation Factors: Implications for Translation Regulation and Evolution of the Translation System
    L. Aravind
    Eugene V. Koonin
    First Published August 1, 2000
  - Ecologic Genomics of DNA: Upstream Bending in Prokaryotic Promoters
    Alexander Bolshoy
    Eviatar Nevo
    First Published August 1, 2000
  - Genomic Sequence Analysis of Fugu rubripes CFTR and Flanking Genes in a 60 kb Region Conserving Synteny with 800 kb of Human Chromosome 7
    Heather Davidson
    Martin S. Taylor
    Ann Doherty
    A. Christopher Boyd
    David J. Porteous
    First Published August 1, 2000
METHODS
- - Predicting Protein Function by Genomic Context: Quantitative Evaluation and Qualitative Inferences
    Martijn Huynen
    Berend Snel
    Warren Lathe
    Peer Bork
    First Published August 1, 2000
  - Loss of Heterozygosity Assay for Molecular Detection of Cancer Using Energy-transfer Primers and Capillary Array Electrophoresis
    Igor L. Medintz
    Chyi-Chia Richard Lee
    Wendy W. Wong
    Kristin Pirkola
    David Sidransky
    Richard A. Mathies
    First Published August 1, 2000
  - High-resolution Quantification of Specific mRNA Levels in Human Brain Autopsies and Biopsies
    Anja Castensson
    Lina Emilsson
    Paul Preece
    and Elena Jazin
    First Published August 1, 2000
  - Tissue Gene Expression Analysis Using Arrayed Normalized cDNA Libraries
    Eickhoff Holger
    Schuchhardt Johannes
    Ivanov Igor
    Meier-Ewert Sebastian
    O'Brien John
    Malik Arif Tandon Neeraj Wolski Eryk-Witold Rohlfs Elke
    ...[+4 authors]...,
    Nyarsik Lajos
    Reinhardt Richard
    Nietfeld Wilfried
    Lehrach Hans
    First Published August 1, 2000
  - A Quantitative Evaluation of SAGE
    Jes Stollberg
    Johann Urschitz
    Zsolt Urban
    Charles D. Boyd
    First Published August 1, 2000
  - Determination of Single-Nucleotide Polymorphisms by Real-time Pyrophosphate DNA Sequencing
    Anders Alderborn
    Anna Kristofferson
    Ulf Hammerling
    First Published August 1, 2000
RESOURCE
- - Expression-based Genetic/Physical Maps of Single-Nucleotide Polymorphisms Identified by the Cancer Genome Anatomy Project
    Robert Clifford
    Michael Edmonson
    Ying Hu
    Cu Nguyen
    Titia Scherpbier
    Kenneth H. Buetow
    First Published August 1, 2000

Table of Contents

Volume 10, Issue 8 | August 2000

INSIGHT/OUTLOOK

A Chimpanzee Genome Project Is a Biomedical Imperative

WABA Success: A Tool for Sequence Comparison between Large Genomes

Guilt by Association: Contextual Information in Genome Analysis

REVIEW

Automation for Genomics, Part One: Preparation for Sequencing

REPORTS

Genomic Sequence Analysis of the Mouse Naip Gene Array

Gene Survey of the Pathogenic Protozoan Trypanosoma cruzi

GT Repeats Are Associated with Recombination on Human Chromosome 22

ARTICLES

Conservation, Regulation, Synteny, and Introns in a Large-scale C. briggsae–C. elegans Genomic Alignment

Genome-wide Detection of Allelic Imbalance Using Human SNPs and High-density DNA Arrays

LETTERS

Discovery of a Novel, Paternally Expressed Ubiquitin-specific Processing Protease Gene through Comparative Analysis of an Imprinted Region of Mouse Chromosome 7 and Human Chromosome 19q13.4

Alfresco—A Workbench for Comparative Genomic Sequence Analysis

High-resolution Genetic and Physical Map of the Lgn1 Interval in C57BL/6J Implicates Naip2 or Naip5 in Legionella pneumophila Pathogenesis

Eukaryote-specific Domains in Translation Initiation Factors: Implications for Translation Regulation and Evolution of the Translation System

Ecologic Genomics of DNA: Upstream Bending in Prokaryotic Promoters

Genomic Sequence Analysis of Fugu rubripes CFTR and Flanking Genes in a 60 kb Region Conserving Synteny with 800 kb of Human Chromosome 7

METHODS

Predicting Protein Function by Genomic Context: Quantitative Evaluation and Qualitative Inferences

Loss of Heterozygosity Assay for Molecular Detection of Cancer Using Energy-transfer Primers and Capillary Array Electrophoresis

High-resolution Quantification of Specific mRNA Levels in Human Brain Autopsies and Biopsies

Tissue Gene Expression Analysis Using Arrayed Normalized cDNA Libraries

A Quantitative Evaluation of SAGE

Determination of Single-Nucleotide Polymorphisms by Real-time Pyrophosphate DNA Sequencing

RESOURCE

Expression-based Genetic/Physical Maps of Single-Nucleotide Polymorphisms Identified by the Cancer Genome Anatomy Project

Table of Contents

Volume 10, Issue 8 | August 2000

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INSIGHT/OUTLOOK

REVIEW

REPORTS

ARTICLES

LETTERS

METHODS

RESOURCE