Large-Scale Comparison of Fungal Sequence Information: Mechanisms of Innovation in Neurospora crassa and Gene Loss in Saccharomyces cerevisiae

Table 7.

N. crassa Genes with Homologs in NF but Not HMEST

Discontig Identification NF E-value EUTH E-value
II. Cell signaling/cell communication
  226 Tap42p protein phosphatase subunit 10−6  10−4  
IV. Cell/organism defense
  359 low temperature and salt induced protein 3 × 10−10
 1069 nitrilase 9 × 10−11
V. Metabolism
   10 thiamine-repressed protein (NMT1) 10−23
  192 thiamine biosynthetic enzyme 9 × 10−37
  197 amino acid permease (AAP2) 10−6 
  266 fructose 1,6-bisphosphate aldolase 4 × 10−18
  287 laccase (LAC1) 2 × 10−7
  367 methionine synthase (Met6p) 10−41
  368 nitrite reductase 4 × 10−22
  445 putative hydrolase 2 × 10−7 0.02 
  466 formate dehydrogenase 5 × 10−11
  525 peptide transporter (Ptr2p) 2 × 10−11 5 × 10−5
  611 phosphatidylserine synthase 2 × 10−8 0.014
  637 sulfite reductase 5 × 10−10
  815 isocitrate lyase (ACU-3) 2 × 10−19
  880 α-amylase 10−5 
  935 pyruvate-formate lyase activating enzyme 8 × 10−10
  957 Ca2+/H+ exchanger (Vcx1p) 10−22
  962 Putative oxidoreductase 2 × 10−12
  980 Δ24-sterol C-methyltransferase (Erg6p) 2 × 10−21
 1011 pyruvate decarboxylase 2 × 10−19
 1058 NADP-dependent glutamate dehydrogenase (AM) 2 × 10−12
 1105 cystathionine beta-synthase (Cys4p) 4 × 10−6
VI. Protein synthesis
   82 subtilisin-like serine proteinase 7 × 10−13
Unclassified
  340 ethylene-forming enzyme 2 × 10−7
  467 hypothetical protein, Streptomyces coelicolor 4 × 10−7
  667 flavohemoglobin (Yhb1p) 5 × 10−10
 1053 carbonic anhydrase 5 × 10−22
 1175 homolog of Dem gene product from plants 5 × 10−7 0.057
 1179 hypothetical protein, Synechocystissp. 2 × 10−31
  • All sequences have no hit in the human/mouse EST data set (no E-value < 0.1).

  • E-value of best BLAST hit in nonfungal data set.

  • E-value of best BLAST hit in eutherian data set.

  • Functional categories are as described in Nelson et al. (1997), based on a modification of the system described by White and Kerlavage (1996).

  • This discontig has a possible hit (E-value < 0.1) in C. elegans.

  • No eutherian database sequence received anE-value < 0.1.

This Article

  1. Genome Res. 10: 416-430

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