Large-Scale Comparison of Fungal Sequence Information: Mechanisms of Innovation in Neurospora crassa and Gene Loss in Saccharomyces cerevisiae

Table 5.

Candidates for Horizontal Gene Transfer into N. crassa:Discontigs with Apparent Orthologs Only in Prokaryotes

Discontig Identification Prok E-value SC E-value Euk E-value
IV. Cell/organism defense
  435 catalase T (catalase-peroxidase) 6 × 10−48  —
 1069 nitrilase 9 × 10−11
V. Metabolism
   94 salicylate 1-monooxygenase 7 × 10−11 3 × 10−5
  163 2,5-DDOL dehydrogenase 10−20 2 × 10−10 10−16  
  256 polyketide synthase PKS1 2 × 10−17 2 × 10−6
  351 putative 2-nitropropane dioxygenase 4 × 10−6
  443 putative amidohydrolase 9 × 10−16 0.006
  698 cytochrome P-450nor2 4 × 10−14
  935 pyruvate-formulate lyase activating enzyme 8 × 10−10
  947 meta-cleavage dioxygenase 2 × 10−21
Unclassified
  118 hypothetical protein,B. subtilis 3 × 10−7
  340 ethylene-forming enzyme 2 × 10−7
 1179 hypothetical protein, Synechocystissp. 2 × 10−31 0.094
  • E-value of best BLAST hit for a prokaryotic organism in the nonfungal data set.

  • E-value of best BLAST hit in S. cerevisiae data set.

  • E-value of best BLAST hit to a eukaryotic organism in the nonfungal data set.

  • Functional categories are as described in Nelson et al. (1997), based on a modification of the system described by White and Kerlavage (1996).

  • No S. cerevisiae database sequence received anE-value < 0.1.

  • No sequence from a eukaryotic organism in the nonfungal database received an E-value < 0.1.

  • These sequences have homologs in A. nidulans.

  • This sequence has an S. pombe homolog (E-value = 9 × 10−19).

This Article

  1. Genome Res. 10: 416-430

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