Fungal-Specific Genes Present in the NGP Data Set
| Discontig | Identification | SC E-value | Fungal distribution |
| III. Cell structure/cytoskeleton | |||
| 34 | YOL030w | 3 × 10−54 | Sp, Ca, En |
| 439 | Gas1p (YMR307wd) | 3 × 10−32 | Sp, Ca, En |
| 1133 | Pir1p (YKL164c) | 4 × 10−11 | Ca |
| V. Metabolism | |||
| 1003 | Fth1p (YBR207w) | 3 × 10−26 | Sp, Ca |
| VII. RNA synthesis | |||
| 231 | Ecm22p (YLR228c) | 5 × 10−7 | Sp, Ca, En |
| 489 | Sok2p (YMR016c) | 4 × 10−23 | Sp, Ca, En |
| Unclassified | |||
| 469 | YGR033c | 2 × 10−14 | Sp, Ca |
| 812 | YOL048c | 4 × 10−8 | Ca |
| 828 | YOR081c | 3 × 10−7 | Sp, Ca |
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↵ E-value of best BLAST hit against S. cerevisiae data set. E-value of best BLAST hit against nonfungal datasets is >0.1.
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↵Distribution of homologs within the fungi based on BLAST searches. (Sp) S. pombe; (Ca) C. albicans; (En)A. nidulans. None of these sequences have clear homologs in the sequences available from nonascomycete fungi.
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↵Functional categories are as described in Nelson et al. (1997), based on a modification of the system described by White and Kerlavage (1996).
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↵These sequences [N. crassa discontigs 34 and 439 and S. cerevisiae Gas1p (YMR307w) and YOL030w] correspond to paralogous fungal-specific genes encoding glycophospholipid-anchored surface proteins. Gas1p has a weak nonfungal hit, corresponding to a putative A. thaliana β-1,3-glucanase (for details, seePopolo and Vai 1999).
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↵The absence of a S. pombe Pir1p homolog may be more than incomplete sampling, because previous studies were unable to identify fragments hybridizing to the PIR1 gene in S. pombe (Toh-e et al. 1993).
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↵Discontig 489 corresponded to the Asm-1 + gene, which has been shown to encode an APSES-domain transcription factor homologous to the S. cerevisiae Sok2p protein (Aramayo et al. 1996).
