Rates of divergence are similar for N. crassa and S. cerevisiae. Pairs of homologous N. crassa and S. cerevisiae sequences were analyzed using BLAST against NF (a database of nonfungal protein sequences); each pair is represented by a point in the plot, with the x-axis showing the negative log of the E-value [−log (E)] of the best database match to the N. crassa query and the y-axis showing −log (E) of the best match to the S. cerevisiaequery. (○) Pairs for which the N. crassa sequence was (part of) an EST from our data set; in these cases, the N. crassa contig and the paired S. cerevisiae sequence were trimmed to the region of overlap, as described in Methods. (●) Pairs for which the N. crassa and S. cerevisiae sequences were complete protein sequences. The outlying point in this plot, labeled “γ,” is γ-tubulin (see text).
