The Genomic Region Encompassing the Nephropathic Cystinosis Gene (CTNS): Complete Sequencing of a 200-kb Segment and Discovery of a Novel Gene within the Common Cystinosis-Causing Deletion

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Figure 3.
Figure 3.

Genomic structure of CARKL. A detailed view of the intron/exon organization of CARKL is provided. Each of the seven exons is depicted to scale, with the hatched regions corresponding to the predicted ORF. Available 3′ and 5′ ESTs from the terminal exon (GenBank accession nos. indicated) are depicted. GRAIL2- and GENSCAN-predicted exons are indicated (top). The asterisks indicate cases where GRAIL2 incorrectly predicts the location of utilized splice sites. The CARKL mRNA sequence is provided in GenBank accession no. AF163573.

This Article

  1. Genome Res. 10: 165-173

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