BAC-based STS-content map of the region of chromosome 17p13 containingCTNS. A fully contiguous BAC contig map spanning the genomic segment encompassing CTNS is depicted, oriented with 17pter leftward and 17cen rightward. Shown along the top are the deduced positions of 43 STSs (spaced in an equidistant fashion from one another). Information about the STSs and their corresponding PCR assays is available in GenBank and/or GDB. Genetic markers are indicated by their D17S numbers, the one gene-specific STS by its assigned abbreviation (ASPA), and all the other STSs by their GenBank accession numbers. BACs are depicted as horizontal lines, with the length of each line reflecting the clone's STS content (as opposed to its insert size). The BAC names include the following prefixes reflecting the clone's library of origin: (RG) Research Genetics human BAC library; (GS) Genome Systems human BAC library; and (NH) Roswell Park Cancer Institute human BAC library RPCI-11. (●) The STS was verified to be present in that clone by PCR testing; (◼) the STS was derived from the insert end of that BAC. The two BACs subjected to complete sequencing (see Fig. 2), which together contain the entireCTNS gene, are contained within a dashed box.
