Comparative Genome Analysis of the Mouse Imprinted Gene Impact and Its Nonimprinted Human Homolog IMPACT: Toward the Structural Basis for Species-Specific Imprinting

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Figure 5.
Figure 5.

Genomic organizations of mouse Impact and humanIMPACT. Physical maps of mouse and human genes are shown in (A) and (B), respectively. Minimum contig of the subclones to cover each gene is also shown. PCR and direct sequencing closed a gap between human subclones 4 × 32 and 4 × 03. Exons are shown as solid boxes and numbered 1 to 11. Arrows indicate the initiation and termination codons. The positions of SINES, LINE-1, CpG islands, and STSs used for the library screening are also illustrated.

This Article

  1. Genome Res. 10: 1878-1889

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