Comparative Genome Analysis of the Mouse Imprinted Gene Impact and Its Nonimprinted Human Homolog IMPACT: Toward the Structural Basis for Species-Specific Imprinting

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Figure 2.
Figure 2.

Chromosomal localization of human IMPACT. (A) FISH analysis of human chromosomes with a biotinylated IMPACT cDNA probe. The doublet signals on both of the chromosome 18s were seen in 4 cells, and the singlet signals on one of the chromosome 18s were found in 19 metaphase cells of the 54 cells inspected. No other hybridization signals were detected. The arrows indicate the doublet signals. (B) G-Banded pattern of the same cell. (C) Idiogram of human chromosome 18 with the location of the IMPACTlocus.

This Article

  1. Genome Res. 10: 1878-1889

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