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Single-nucleus multiomic profiling of the aging mouse substantia nigra reveals conserved gene alterations linked to Parkinson's disease
Kangli Wang
,
Weikun Xia
,
Yingli Gu
,
Songpeng Zu
,
Qian Yang
,
Maria Luisa Amaral
,
Yaozhi Wang
,
Allen Wang
,
Xiang-Dong Fu
,
William C. Mobley
,
and
Bing Ren
Genome Res.
March 4, 2026
gr.281113.125
;
Published in Advance
March 4, 2026
,
doi:
10.1101/gr.281113.125
Abstract
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Cell type–specific gene regulatory atlas prioritizes drug targets and repurposable medicines in Alzheimer's disease
Yunxiao Ren
,
Ming Hu
,
Yang E. Li
,
Andrew A. Pieper
,
Jeffrey Cummings
,
and
Feixiong Cheng
Genome Res.
March 2026
36
:
645
-
659
;
Published in Advance
January 21, 2026
,
doi:
10.1101/gr.280436.125
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The SynMall resource for characterizing the functional impact of synonymous variation
Chen Ye
,
Xiaoyan Li
,
Na Cheng
,
Yansen Su
,
and
Junfeng Xia
Genome Res.
February 2026
36
:
421
-
431
;
Published in Advance
December 17, 2025
,
doi:
10.1101/gr.281257.125
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A systems view on DNA damage response kinetics in
Tetrahymena
Emily Nischwitz
,
Vivien Schoonenberg
,
Rachel Mullner
,
Albert Fradera-Sola
,
Susanne Zimbelmann
,
Joshua J Smith
,
and
Falk Butter
Genome Res.
January 28, 2026
gr.281000.125
;
Published in Advance
January 28, 2026
,
doi:
10.1101/gr.281000.125
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The PanOryza pangene catalog of Asian cultivated rice
Bruno Contreras-Moreira
,
Eshan Sharma
,
Shradha Saraf
,
Guy Naamati
,
Parul Gupta
,
Justin Elser
,
Dmytro Chebotarov
,
Kapeel Chougule
,
Zhenyuan Lu
,
Sharon Wei
,
Andrew Olson
,
Ian Tsang
,
Disha Lodha
,
Yong Zhou
,
Zhichao Yu
,
Wen Zhao
,
Jianwei Zhang
,
Sandeep Amberkar
,
Kawinnat Sue-Ob
,
Zhi Sun
,
Maria Martin
,
Kenneth L. McNally
,
Doreen Ware
,
Eric W. Deutsch
,
Dario Copetti
,
Rod A. Wing
,
Pankaj Jaiswal
,
Sarah Dyer
,
and
Andrew R. Jones
Genome Res.
January 2026
36
:
226
-
238
;
Published in Advance
December 12, 2025
,
doi:
10.1101/gr.280790.125
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Epigenomics of embryogenesis in turbot
Oscar Aramburu
,
Belen G Pardo
,
Ada Jimenez-Gonzalez
,
Andrés Blanco-Hortas
,
Daniel Macqueen
,
Carmen Bouza
,
and
Paulino Martinez
Genome Res.
November 4, 2025
gr.280355.124
;
Published in Advance
November 4, 2025
,
doi:
10.1101/gr.280355.124
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Quadrupia provides a comprehensive catalog of G-quadruplexes across genomes from the tree of life
Nikol Chantzi
,
Akshatha Nayak
,
Fotis A. Baltoumas
,
Eleni Aplakidou
,
Shiau Wei Liew
,
Jesslyn Elvaretta Galuh
,
Michail Patsakis
,
Austin Montgomery
,
Camille Moeckel
,
Ioannis Mouratidis
,
Saiful Arefeen Sazed
,
Wilfried Guiblet
,
Panagiotis Karmiris-Obratański
,
Guliang Wang
,
Apostolos Zaravinos
,
Karen M. Vasquez
,
Chun Kit Kwok
,
Georgios A. Pavlopoulos
,
and
Ilias Georgakopoulos-Soares
Genome Res.
November 2025
35
:
2578
-
2600
;
Published in Advance
August 26, 2025
,
doi:
10.1101/gr.279790.124
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High-quality assembly of the Chinese white truffle genome and recalibrated divergence time estimate provide insight into the evolutionary dynamics of Tuberaceae
Jacopo Martelossi
,
Jacopo Vujovic
,
Yue Huang
,
Alessia Tatti
,
Kaiwei Xu
,
Federico Puliga
,
Yuanxue Chen
,
Omar Rota Stabelli
,
Fabrizio Ghiselli
,
Xiaoping Zhang
,
and
Alessandra Zambonelli
Genome Res.
November 2025
35
:
2601
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2616
;
Published in Advance
August 21, 2025
,
doi:
10.1101/gr.280368.124
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Integrative chromatin state annotation of 234 human ENCODE4 cell types using Segway
Marjan Farahbod
,
Aboud Diab
,
Paul Sud
,
Meenakshi S. Kagda
,
Ian Whaling
,
Mehdi Foroozandeh
,
Ishan Goel
,
Habib Daneshpajouh
,
Benjamin Hitz
,
J. Michael Cherry
,
and
Maxwell W. Libbrecht
Genome Res.
October 6, 2025
gr.280633.125
;
Published in Advance
October 6, 2025
,
doi:
10.1101/gr.280633.125
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Analyzing the large and complex SFARI autism cohort data using the Genotypes and Phenotypes in Families (GPF) platform
Liubomir Chorbadjiev
,
Murat Cokol
,
Zohar Weinstein
,
Kevin Shi
,
Christopher Fleisch
,
Nikolay Dimitrov
,
Svetlin Mladenov
,
Ivo Todorov
,
Iordan Ivanov
,
Simon Xu
,
Steven Ford
,
Yoon-ha Lee
,
Boris Yamrom
,
Steven Marks
,
Adriana Munoz
,
Alex Lash
,
Natalia Volfovsky
,
and
Ivan Iossifov
Genome Res.
October 2025
35
:
2352
-
2362
;
Published in Advance
September 16, 2025
,
doi:
10.1101/gr.280356.124
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Single-cell gene signature scoring
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Short tandem repeat genotyping using long reads
Spectral component approach for recent population structure
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