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Research

Derepression of Polycomb targets during pancreatic organogenesis allows insulin-producing beta-cells to adopt a neural gene activity program

  • First Published April 15, 2010
Method

Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities

  • First Published April 8, 2010
Research

Rickettsia prowazekii reveals its adaptive mutation capabilities" > Genomic, proteomic, and transcriptomic analysis of virulent and avirulent Rickettsia prowazekii reveals its adaptive mutation capabilities

  • First Published April 5, 2010
Research

Global survey of escape from X inactivation by RNA-sequencing in mouse

  • First Published April 2, 2010
Research

Homotypic clusters of transcription factor binding sites are a key component of human promoters and enhancers

  • First Published April 2, 2010
Research

mRNA deep sequencing reveals 75 new genes and a complex transcriptional landscape in Mimivirus

  • First Published April 1, 2010
Research

Copy number variation, chromosome rearrangement, and their association with recombination during avian evolution

  • First Published March 31, 2010
Research

Pronounced inter- and intrachromosomal variation in linkage disequilibrium across the zebra finch genome

  • First Published March 31, 2010
Research

Sex bias and dosage compensation in the zebra finch versus chicken genomes: General and specialized patterns among birds

  • First Published March 31, 2010
Research

Taeniopygia guttata genome" > The recombination landscape of the zebra finch Taeniopygia guttata genome

  • First Published March 31, 2010
Research

Drosophila revealed by mRNA-seq" > Regulatory divergence in Drosophila revealed by mRNA-seq

  • First Published March 30, 2010
Research

Natural selection drives the accumulation of amino acid tandem repeats in human proteins

  • First Published March 24, 2010
Research

Genome-wide mapping and assembly of structural variant breakpoints in the mouse genome

  • First Published March 22, 2010
Method

Genome assembly quality: Assessment and improvement using the neutral indel model

  • First Published March 19, 2010
Research

Deep RNA sequencing at single base-pair resolution reveals high complexity of the rice transcriptome

  • First Published March 19, 2010
Research

Pristionchus pacificus reveals distinct proteome structure of nematode models" > Proteogenomics of Pristionchus pacificus reveals distinct proteome structure of nematode models

  • First Published March 17, 2010
Research

The (r)evolution of SINE versus LINE distributions in primate genomes: Sex chromosomes are important

  • First Published March 10, 2010
Research

Rewirable gene regulatory networks in the preimplantation embryonic development of three mammalian species

  • First Published March 10, 2010
Research

A CTCF-independent role for cohesin in tissue-specific transcription

  • First Published March 10, 2010
Research

Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer

  • First Published March 10, 2010
Method

Integrating multiple evidence sources to predict transcription factor binding in the human genome

  • First Published March 10, 2010
Research

Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains

  • First Published March 10, 2010
Research

Ciona intestinalis SL trans-spliced mRNAs: Alternative expression modes and gene function correlates" > High-throughput sequence analysis of Ciona intestinalis SL trans-spliced mRNAs: Alternative expression modes and gene function correlates

  • First Published March 8, 2010
Research

The effect of translocation-induced nuclear reorganization on gene expression

  • First Published March 8, 2010
Resource

Analysis of copy number variations among diverse cattle breeds

  • First Published March 8, 2010
Research

Coexpression network analysis of neural tissue reveals perturbations in developmental processes in schizophrenia

  • First Published March 2, 2010
RESOURCE

An effective model for natural selection in promoters

  • First Published March 1, 2010
Research

Genome-wide analysis of histone modifications in human pancreatic islets

  • First Published February 24, 2010
Research

Integrative analysis of the melanoma transcriptome

  • First Published February 23, 2010
Resource

Accurate detection and genotyping of SNPs utilizing population sequencing data

  • First Published February 11, 2010
Methods

Inference of RhoGAP/GTPase regulation using single-cell morphological data from a combinatorial RNAi screen

  • First Published February 9, 2010
Method

Digital transcriptome profiling from attomole-level RNA samples

  • First Published February 4, 2010
Letter

Dynamic changes in the human methylome during differentiation

  • First Published February 4, 2010
Methods

A new strategy for genome assembly using short sequence reads and reduced representation libraries

  • First Published February 1, 2010
Letter

ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells

  • First Published January 28, 2010
Letter

Widespread and tissue specific age-related DNA methylation changes in mice

  • First Published January 27, 2010
Research

Impact of replication timing on non-CpG and CpG substitution rates in mammalian genomes

  • First Published January 26, 2010
Letter

Copy number abnormalities in sporadic canine colorectal cancers

  • First Published January 19, 2010
Methods

Population differentiation as a test for selective sweeps

  • First Published January 19, 2010
Methods

Genome-wide discovery of human heart enhancers

  • First Published January 14, 2010
Review

Population genetic inference from genomic sequence variation

  • First Published January 12, 2010
Letter

Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes

  • First Published January 12, 2010
Research

Genome-wide evidence for selection acting on single amino acid repeats

  • First Published January 7, 2010
Resource

A high-resolution association mapping panel for the dissection of complex traits in mice

  • First Published January 6, 2010
Letter

Nucleosome landscape and control of transcription in the human malaria parasite

  • First Published January 6, 2010
Methods

Cross-mapping and the identification of editing sites in mature microRNAs in high-throughput sequencing libraries

  • First Published January 5, 2010
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