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Research

Stable and dynamic nucleosome states during a meiotic developmental process

  • First Published April 22, 2011
Research

Slc35b4, regulates obesity and glucose homeostasis" > Deep congenic analysis identifies many strong, context-dependent QTLs, one of which, Slc35b4, regulates obesity and glucose homeostasis

  • First Published April 19, 2011
Resource

A method for detecting IBD regions simultaneously in multiple individuals—with applications to disease genetics

  • First Published April 14, 2011
Research

Aspergillus fumigatus infection" > Collaborative Cross mice and their power to map host susceptibility to Aspergillus fumigatus infection

  • First Published April 14, 2011
Research

KIF1A in hereditary spastic paraparesis" > Exome sequencing and disease-network analysis of a single family implicate a mutation in KIF1A in hereditary spastic paraparesis

  • First Published April 12, 2011
Resource

ECHO: A reference-free short-read error correction algorithm

  • First Published April 11, 2011
Research

Origin of amphibian and avian chromosomes by fission, fusion, and retention of ancestral chromosomes

  • First Published April 11, 2011
Method

Characterization of metalloproteins by high-throughput X-ray absorption spectroscopy

  • First Published April 11, 2011
Method

Differential genome-wide profiling of tandem 3′ UTRs among human breast cancer and normal cells by high-throughput sequencing

  • First Published April 7, 2011
Method

Calling Cards enable multiplexed identification of the genomic targets of DNA-binding proteins

  • First Published April 6, 2011
Research

Diverse gene reprogramming events occur in the same spatial clusters of distal regulatory elements

  • First Published April 6, 2011
Research

Arabidopsis thaliana" > Genetic architecture of regulatory variation in Arabidopsis thaliana

  • First Published April 5, 2011
Research

Neurons show distinctive DNA methylation profile and higher interindividual variations compared with non-neurons

  • First Published April 5, 2011
Research

Transcriptional consequences of genomic structural aberrations in breast cancer

  • First Published April 5, 2011
Research

Comprehensive long-span paired-end-tag mapping reveals characteristic patterns of structural variations in epithelial cancer genomes

  • First Published April 5, 2011
Research

Natural genetic variation caused by small insertions and deletions in the human genome

  • First Published April 1, 2011
Resource

Low-coverage sequencing: Implications for design of complex trait association studies

  • First Published April 1, 2011
Method

Shotgun proteomics aids discovery of novel protein-coding genes, alternative splicing, and “resurrected” pseudogenes in the mouse genome

  • First Published April 1, 2011
Resource

MicroRNA programs in normal and aberrant stem and progenitor cells

  • First Published March 30, 2011
Method

Detection of common single nucleotide polymorphisms synthesizing quantitative trait association of rarer causal variants

  • First Published March 25, 2011
Method

Revealing the genetic structure of a trait by sequencing a population under selection

  • First Published March 21, 2011
Research

Genetic analysis of complex traits in the emerging Collaborative Cross

  • First Published March 15, 2011
Research

RAF gene fusion breakpoints in pediatric brain tumors are characterized by significant enrichment of sequence microhomology" > RAF gene fusion breakpoints in pediatric brain tumors are characterized by significant enrichment of sequence microhomology

  • First Published March 10, 2011
Research

Recurrence, submicroscopic complexity, and potential clinical relevance of copy gains detected by array CGH that are shown to be unbalanced insertions by FISH

  • First Published March 7, 2011
Research

Drosophila embryos: Efficient functional analysis and evolutionary conservation" > High resolution mapping of Twist to DNA in Drosophila embryos: Efficient functional analysis and evolutionary conservation

  • First Published March 7, 2011
Research

Genes for embryo development are packaged in blocks of multivalent chromatin in zebrafish sperm

  • First Published March 7, 2011
Resource

Genome-wide characterization of transcriptional start sites in humans by integrative transcriptome analysis

  • First Published March 3, 2011
Research

C. elegans" > Core promoter T-blocks correlate with gene expression levels in C. elegans

  • First Published March 2, 2011
Method

Discovery and annotation of small proteins using genomics, proteomics, and computational approaches

  • First Published March 2, 2011
Research

Nucleosome fragility reveals novel functional states of chromatin and poises genes for activation

  • First Published March 1, 2011
Method

High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome

  • First Published March 1, 2011
Resource

Exhaustive T-cell repertoire sequencing of human peripheral blood samples reveals signatures of antigen selection and a directly measured repertoire size of at least 1 million clonotypes

  • First Published February 24, 2011
Method

Biome representational in silico karyotyping

  • First Published February 10, 2011
Resource

Maximum-likelihood estimation of recent shared ancestry (ERSA)

  • First Published February 8, 2011
Resource

CNVnator: An approach to discover, genotype, and characterize typical and atypical CNVs from family and population genome sequencing

  • First Published February 7, 2011
Method

A novel approach identifies new differentially methylated regions (DMRs) associated with imprinted genes

  • First Published February 7, 2011
Perspective

Gene regulatory networks and the role of robustness and stochasticity in the control of gene expression

  • First Published February 4, 2011
Research

Coordinated histone modifications are associated with gene expression variation within and between species

  • First Published February 4, 2011
Research

Dioxin receptor and SLUG transcription factors regulate the insulator activity of B1 SINE retrotransposons via an RNA polymerase switch

  • First Published February 3, 2011
Method

Sequence-based physical mapping of complex genomes by whole genome profiling

  • First Published February 1, 2011
Research

Comparative methylome analysis of benign and malignant peripheral nerve sheath tumors

  • First Published February 1, 2011
Research

Directed networks reveal genomic barriers and DNA repair bypasses to lateral gene transfer among prokaryotes

  • First Published January 26, 2011
Research

Incomplete lineage sorting patterns among human, chimpanzee, and orangutan suggest recent orangutan speciation and widespread selection

  • First Published January 26, 2011
Research

Large duplications at reciprocal translocation breakpoints that might be the counterpart of large deletions and could arise from stalled replication bubbles

  • First Published January 20, 2011
Method

Efficient storage of high throughput DNA sequencing data using reference-based compression

  • First Published January 18, 2011
Research

Drosophila melanogaster TORC1–S6K pathway signaling" > Genome-scale RNAi on living-cell microarrays identifies novel regulators of Drosophila melanogaster TORC1–S6K pathway signaling

  • First Published January 14, 2011
Research

Epigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancers

  • First Published January 13, 2011
Method

Multiplexed shotgun genotyping for rapid and efficient genetic mapping

  • First Published January 13, 2011
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