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Research

Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes

  • First Published November 21, 2011
Research

DMD gene" > Aberrant firing of replication origins potentially explains intragenic nonrecurrent rearrangements within genes, including the human DMD gene

  • First Published November 16, 2011
Research

Interlocus gene conversion events introduce deleterious mutations into at least 1% of human genes associated with inherited disease

  • First Published November 16, 2011
Research

Cell-type specific and combinatorial usage of diverse transcription factors revealed by genome-wide binding studies in multiple human cells

  • First Published November 16, 2011
Research

Developmental control of gene copy number by repression of replication initiation and fork progression

  • First Published November 16, 2011
Method

Preparation of high-quality next-generation sequencing libraries from picogram quantities of target DNA

  • First Published November 16, 2011
Method

Calling amplified haplotypes in next generation tumor sequence data

  • First Published November 16, 2011
Research

Tumor-specific retargeting of an oncogenic transcription factor chimera results in dysregulation of chromatin and transcription

  • First Published November 15, 2011
Research

Lactococcus lactis can be reproduced by experimental evolution" > Microbial domestication signatures of Lactococcus lactis can be reproduced by experimental evolution

  • First Published November 11, 2011
Resource

Simultaneous structural variation discovery among multiple paired-end sequenced genomes

  • First Published November 2, 2011
Research

Deep-transcriptome and ribonome sequencing redefines the molecular networks of pluripotency and the extracellular space in human embryonic stem cells

  • First Published October 31, 2011
Research

Locus- and domain-dependent control of DNA methylation at mouse B1 retrotransposons during male germ cell development

  • First Published October 31, 2011
Research

Leishmania" > Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania

  • First Published October 28, 2011
Research

Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance" > Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance

  • First Published October 28, 2011
Research

Fusobacterium with colorectal carcinoma" > Genomic analysis identifies association of Fusobacterium with colorectal carcinoma

  • First Published October 18, 2011
Research

Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma" > Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma

  • First Published October 18, 2011
Research

Compensation for differences in gene copy number among yeast ribosomal proteins is encoded within their promoters

  • First Published October 18, 2011
Research

PRDM9 coincides with stabilization of the recombination landscape in the dog genome" > Death of PRDM9 coincides with stabilization of the recombination landscape in the dog genome

  • First Published October 17, 2011
Research

Drosophila and other metazoa" > Evidence of abundant stop codon readthrough in Drosophila and other metazoa

  • First Published October 12, 2011
Method

Locating protein-coding sequences under selection for additional, overlapping functions in 29 mammalian genomes

  • First Published October 12, 2011
Method

New families of human regulatory RNA structures identified by comparative analysis of vertebrate genomes

  • First Published October 12, 2011
Research

Mycosphaerella graminicola and its wild sister species" > The making of a new pathogen: Insights from comparative population genomics of the domesticated wheat pathogen Mycosphaerella graminicola and its wild sister species

  • First Published October 12, 2011
Method

Estimation of rearrangement phylogeny for cancer genomes

  • First Published October 12, 2011
Research

A matter of life or death: How microsatellites emerge in and vanish from the human genome

  • First Published October 12, 2011
Research

Unique DNA methylome profiles in CpG island methylator phenotype colon cancers

  • First Published October 11, 2011
Research

Genomic analysis of circulating cell-free DNA infers breast cancer dormancy

  • First Published October 11, 2011
Research

Changes in exon–intron structure during vertebrate evolution affect the splicing pattern of exons

  • First Published October 5, 2011
Research

Populus" > Contrasting patterns of evolution following whole genome versus tandem duplication events in Populus

  • First Published October 5, 2011
Method

Accurate identification of A-to-I RNA editing in human by transcriptome sequencing

  • First Published September 29, 2011
Research

Late-replicating heterochromatin is characterized by decreased cytosine methylation in the human genome

  • First Published September 28, 2011
Research

Extensive variation and low heritability of DNA methylation identified in a twin study

  • First Published September 26, 2011
Research

Genomic basis of endosymbiont-conferred protection against an insect parasitoid

  • First Published September 23, 2011
Research

Post-transcriptional exon shuffling events in humans can be evolutionarily conserved and abundant

  • First Published September 23, 2011
Resource

Arabidopsis" > High-resolution experimental and computational profiling of tissue-specific known and novel miRNAs in Arabidopsis

  • First Published September 22, 2011
Research

Drosophila predicts DNA methylation and CpG landscapes in other invertebrates" > Comparative methylomics reveals gene-body H3K36me3 in Drosophila predicts DNA methylation and CpG landscapes in other invertebrates

  • First Published September 22, 2011
Method

Integrating genetic and gene expression evidence into genome-wide association analysis of gene sets

  • First Published September 22, 2011
Research

A genomic model of condition-specific nucleosome behavior explains transcriptional activity in yeast

  • First Published September 19, 2011
Resource

Assemblathon 1: A competitive assessment of de novo short read assembly methods

  • First Published September 16, 2011
Method

Mutual exclusivity analysis identifies oncogenic network modules

  • First Published September 9, 2011
Research

Phyloepigenomic comparison of great apes reveals a correlation between somatic and germline methylation states

  • First Published September 9, 2011
Research

Widespread signatures of recent selection linked to nucleosome positioning in the human lineage

  • First Published September 8, 2011
Resource

Differential expression in RNA-seq: A matter of depth

  • First Published September 8, 2011
Method

A metabolomic and systems biology perspective on the brain of the Fragile X syndrome mouse model

  • First Published September 7, 2011
Method

Characterization of complex chromosomal rearrangements by targeted capture and next-generation sequencing

  • First Published September 2, 2011
Research

Genome-wide analysis distinguishes hyperglycemia regulated epigenetic signatures of primary vascular cells

  • First Published September 2, 2011
Research

Homozygosity mapping and targeted genomic sequencing reveal the gene responsible for cerebellar hypoplasia and quadrupedal locomotion in a consanguineous kindred

  • First Published September 1, 2011
Erratum

Erratum

  • First Published September 1, 2011
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