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Research

DNA replication and transcription programs respond to the same chromatin cues

  • First Published July 1, 2014
Research

Evolution of H3K27me3-marked chromatin is linked to gene expression evolution and to patterns of gene duplication and diversification

  • First Published July 1, 2014
Method

MultiBLUP: improved SNP-based prediction for complex traits

  • First Published June 24, 2014
Research

Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape

  • First Published June 24, 2014
Research

Reconfiguration of nucleosome-depleted regions at distal regulatory elements accompanies DNA methylation of enhancers and insulators in cancer

  • First Published June 10, 2014
Research

Novel H3K4me3 marks are enriched at human- and chimpanzee-specific cytogenetic structures

  • First Published June 10, 2014
Research

Methane yield phenotypes linked to differential gene expression in the sheep rumen microbiome

  • First Published June 6, 2014
Research

Genomic evidence for adaptation by gene duplication

  • First Published June 5, 2014
Resource

Digital expression profiling of the compartmentalized translatome of Purkinje neurons

  • First Published June 5, 2014
Resource

A cloud-compatible bioinformatics pipeline for ultrarapid pathogen identification from next-generation sequencing of clinical samples

  • First Published June 4, 2014
Erratum

Errata

  • First Published June 1, 2014
Erratum

Errata

  • First Published June 1, 2014
Research

Loss of transcriptional control over endogenous retroelements during reprogramming to pluripotency

  • First Published May 30, 2014
Research

Interplay of TRIM28 and DNA methylation in controlling human endogenous retroelements

  • First Published May 30, 2014
Research

Analysis of 41 plant genomes supports a wave of successful genome duplications in association with the Cretaceous–Paleogene boundary

  • First Published May 16, 2014
Research

The dynamics of DNA methylation fidelity during mouse embryonic stem cell self-renewal and differentiation

  • First Published May 16, 2014
Research

H. melpomene and H. erato" > Population genomics of parallel hybrid zones in the mimetic butterflies, H. melpomene and H. erato

  • First Published May 13, 2014
Research

Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing

  • First Published May 13, 2014
Research

Heritability and genetic basis of protein level variation in an outbred population

  • First Published May 13, 2014
Research

Nucleosome repositioning links DNA (de)methylation and differential CTCF binding during stem cell development

  • First Published May 8, 2014
Method

Single-cell genomics for dissection of complex malaria infections

  • First Published May 8, 2014
Method

Epistasis analysis for quantitative traits by functional regression model

  • First Published May 6, 2014
Research

Natural variation of histone modification and its impact on gene expression in the rat genome

  • First Published May 2, 2014
Research

The impact of widespread regulatory neofunctionalization on homeolog gene evolution following whole-genome duplication in maize

  • First Published April 30, 2014
Research

Neo-antigens predicted by tumor genome meta-analysis correlate with increased patient survival

  • First Published April 29, 2014
Research

Somatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesis

  • First Published April 23, 2014
Resource

Efficient de novo assembly of highly heterozygous genomes from whole-genome shotgun short reads

  • First Published April 22, 2014
Research

Tissue-specific SMARCA4 binding at active and repressed regulatory elements during embryogenesis

  • First Published April 21, 2014
Research

Vascular histone deacetylation by pharmacological HDAC inhibition

  • First Published April 14, 2014
Research

Whole-genome sequencing of six dog breeds from continuous altitudes reveals adaptation to high-altitude hypoxia

  • First Published April 10, 2014
Research

Predicting the virulence of MRSA from its genome sequence

  • First Published April 9, 2014
Research

Dissection of thousands of cell type-specific enhancers identifies dinucleotide repeat motifs as general enhancer features

  • First Published April 8, 2014
Research

Rate of elongation by RNA polymerase II is associated with specific gene features and epigenetic modifications

  • First Published April 8, 2014
Resource

Drosophila melanogaster Genetic Reference Panel lines" > Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines

  • First Published April 8, 2014
Research

The effect of genotype and in utero environment on interindividual variation in neonate DNA methylomes

  • First Published April 7, 2014
Research

cis-regulatory nodes active during the vertebrate phylotypic period" > Comparative epigenomics in distantly related teleost species identifies conserved cis-regulatory nodes active during the vertebrate phylotypic period

  • First Published April 7, 2014
Method

Quantifying ChIP-seq data: a spiking method providing an internal reference for sample-to-sample normalization

  • First Published April 7, 2014
Method

LaSSO, a strategy for genome-wide mapping of intronic lariats and branch points using RNA-seq

  • First Published April 7, 2014
Research

Recurrent epimutations activate gene body promoters in primary glioblastoma

  • First Published April 7, 2014
Method

Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins

  • First Published April 2, 2014
Method

Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA

  • First Published April 2, 2014
In memoriam

Frederick Sanger (1918–2013)

  • First Published April 1, 2014
Resource

Subtelomeric CTCF and cohesin binding site organization using improved subtelomere assemblies and a novel annotation pipeline

  • First Published March 27, 2014
Perspective

Can I be sued for that? Liability risk and the disclosure of clinically significant genetic research findings

  • First Published March 27, 2014
Method

Comparison of CAGE and RNA-seq transcriptome profiling using clonally amplified and single-molecule next-generation sequencing

  • First Published March 27, 2014
Research

Inputs drive cell phenotype variability

  • First Published March 26, 2014
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