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Method

Structured nucleosome fingerprints enable high-resolution mapping of chromatin architecture within regulatory regions

  • First Published August 27, 2015
Research

Integrative analysis of RNA, translation, and protein levels reveals distinct regulatory variation across humans

  • First Published August 21, 2015
Resource

Drosophila by 56 RNA binding proteins" > Regulation of alternative splicing in Drosophila by 56 RNA binding proteins

  • First Published August 20, 2015
Research

DIS3 shapes the RNA polymerase II transcriptome in humans by degrading a variety of unwanted transcripts

  • First Published August 20, 2015
Research

Drosophila" > Extensive cross-regulation of post-transcriptional regulatory networks in Drosophila

  • First Published August 20, 2015
Research

Tandem repeat variation in human and great ape populations and its impact on gene expression divergence

  • First Published August 19, 2015
Resource

Genome-wide annotation of microRNA primary transcript structures reveals novel regulatory mechanisms

  • First Published August 19, 2015
Method

Read clouds uncover variation in complex regions of the human genome

  • First Published August 18, 2015
Research

GC skew defines distinct RNA polymerase pause sites in CpG island promoters

  • First Published August 14, 2015
Research

Widespread somatic L1 retrotransposition occurs early during gastrointestinal cancer evolution

  • First Published August 10, 2015
Research

Genetic and environmental control of host-gut microbiota interactions

  • First Published August 10, 2015
Research

Chlamydomonas reinhardtii" > Extensive de novo mutation rate variation between individuals and across the genome of Chlamydomonas reinhardtii

  • First Published August 10, 2015
Method

The use of exome capture RNA-seq for highly degraded RNA with application to clinical cancer sequencing

  • First Published August 7, 2015
Corrigendum

Corrigendum: MIPSTR: a method for multiplex genotyping of germline and somatic STR variation across many individuals

  • First Published August 3, 2015
Research

Comparison against 186 canid whole-genome sequences reveals survival strategies of an ancient clonally transmissible canine tumor

  • First Published July 31, 2015
Research

C. elegans" > Cooperative target mRNA destabilization and translation inhibition by miR-58 microRNA family in C. elegans

  • First Published July 31, 2015
Research

The frequent evolutionary birth and death of functional promoters in mouse and human

  • First Published July 30, 2015
Method

Discriminating somatic and germline mutations in tumor DNA samples without matching normals

  • First Published July 24, 2015
Research

Aedes aegypti by deep targeted sequencing" > Identifying genomic changes associated with insecticide resistance in the dengue mosquito Aedes aegypti by deep targeted sequencing

  • First Published July 23, 2015
Research

Evolution of selenophosphate synthetases: emergence and relocation of function through independent duplications and recurrent subfunctionalization

  • First Published July 20, 2015
Research

Dynamics and function of distal regulatory elements during neurogenesis and neuroplasticity

  • First Published July 13, 2015
Method

Saturation analysis of ChIP-seq data for reproducible identification of binding peaks

  • First Published July 10, 2015
Research

A widespread role of the motif environment in transcription factor binding across diverse protein families

  • First Published July 9, 2015
Research

SETDB1 modulates PRC2 activity at developmental genes independently of H3K9 trimethylation in mouse ES cells

  • First Published July 9, 2015
Research

Streptococcus equi, is driven by persistent infection" > Genome specialization and decay of the strangles pathogen, Streptococcus equi, is driven by persistent infection

  • First Published July 9, 2015
Research

Functional compensation among HMGN variants modulates the DNase I hypersensitive sites at enhancers

  • First Published July 8, 2015
Research

Germline mutation rates and the long-term phenotypic effects of mutation accumulation in wild-type laboratory mice and mutator mice

  • First Published June 30, 2015
Research

Genome-wide analysis of translational efficiency reveals distinct but overlapping functions of yeast DEAD-box RNA helicases Ded1 and eIF4A

  • First Published June 29, 2015
Research

Acute TNF-induced repression of cell identity genes is mediated by NFκB-directed redistribution of cofactors from super-enhancers

  • First Published June 25, 2015
Research

Comprehensive identification and analysis of human accelerated regulatory DNA

  • First Published June 23, 2015
Method

Massively parallel quantification of the regulatory effects of noncoding genetic variation in a human cohort

  • First Published June 17, 2015
Research

Unbalanced translocations arise from diverse mutational mechanisms including chromothripsis

  • First Published June 12, 2015
Research

Determinants of nucleosome positioning and their influence on plant gene expression

  • First Published June 10, 2015
Research

Sequence determinants of improved CRISPR sgRNA design

  • First Published June 10, 2015
Resource

The landscape of antisense gene expression in human cancers

  • First Published June 10, 2015
Research

Using genome-wide measures of coancestry to maintain diversity and fitness in endangered and domestic pig populations

  • First Published June 10, 2015
Research

Dynamic changes in replication timing and gene expression during lineage specification of human pluripotent stem cells

  • First Published June 8, 2015
Research

The sea lamprey meiotic map improves resolution of ancient vertebrate genome duplications

  • First Published June 5, 2015
Research

Regulation of the ESC transcriptome by nuclear long noncoding RNAs

  • First Published June 5, 2015
Method

High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9

  • First Published June 5, 2015
Research

Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators

  • First Published May 29, 2015
Resource

Hox clusters in ES cells" > Analysis of dynamic changes in retinoid-induced transcription and epigenetic profiles of murine Hox clusters in ES cells

  • First Published May 29, 2015
Research

Topologically associating domains and their long-range contacts are established during early G1 coincident with the establishment of the replication-timing program

  • First Published May 20, 2015
Research

Retrotransposition creates sloping shores: a graded influence of hypomethylated CpG islands on flanking CpG sites

  • First Published May 20, 2015
Method

Quantification of GC-biased gene conversion in the human genome

  • First Published May 20, 2015
Research

Genome-wide activities of Polycomb complexes control pervasive transcription

  • First Published May 18, 2015
Method

CheckM: assessing the quality of microbial genomes recovered from isolates, single cells, and metagenomes

  • First Published May 14, 2015
Research

Core promoter sequence in yeast is a major determinant of expression level

  • First Published May 12, 2015
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