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The pig X and Y Chromosomes: structure, sequence, and evolution

  • First Published November 11, 2015
Research

The chromatin environment shapes DNA replication origin organization and defines origin classes

  • First Published November 11, 2015
Method

INTEGRATE: gene fusion discovery using whole genome and transcriptome data

  • First Published November 10, 2015
Method

Sleeping Beauty transposon-induced tumors detects transposon-RNA fusions in forward genetic cancer screens" > RNA sequencing of Sleeping Beauty transposon-induced tumors detects transposon-RNA fusions in forward genetic cancer screens

  • First Published November 9, 2015
Research

Subcellular RNA profiling links splicing and nuclear DICER1 to alternative cleavage and polyadenylation

  • First Published November 6, 2015
Research

Loss of HP1 causes depletion of H3K27me3 from facultative heterochromatin and gain of H3K27me2 at constitutive heterochromatin

  • First Published November 4, 2015
Research

Nascent RNA folding mitigates transcription-associated mutagenesis

  • First Published October 30, 2015
Research

Tribolium castaneum" > MicroRNA evolution, expression, and function during short germband development in Tribolium castaneum

  • First Published October 30, 2015
Research

Daphnia pulex" > High mutational rates of large-scale duplication and deletion in Daphnia pulex

  • First Published October 30, 2015
Research

Phylogenomic evidence for ancient hybridization in the genomes of living cats (Felidae)

  • First Published October 30, 2015
Research

Active chromatin and transcription play a key role in chromosome partitioning into topologically associating domains

  • First Published October 30, 2015
Research

CAGE profiling of ncRNAs in hepatocellular carcinoma reveals widespread activation of retroviral LTR promoters in virus-induced tumors

  • First Published October 28, 2015
Research

Ribosome profiling reveals the rhythmic liver translatome and circadian clock regulation by upstream open reading frames

  • First Published October 20, 2015
Research

Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/ enhancer-binding protein beta binding sites

  • First Published October 20, 2015
Method

A probabilistic method for testing and estimating selection differences between populations

  • First Published October 13, 2015
Research

An extended family of novel vertebrate photopigments is widely expressed and displays a diversity of function

  • First Published October 8, 2015
Method

Oxford Nanopore sequencing, hybrid error correction, and de novo assembly of a eukaryotic genome

  • First Published October 7, 2015
Research

Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells

  • First Published October 1, 2015
Perspective

The path to routine use of genomic biomarkers in the cancer clinic

  • First Published October 1, 2015
Perspective

Defining cell types and states with single-cell genomics

  • First Published October 1, 2015
Research

Signatures of post-zygotic structural genetic aberrations in the cells of histologically normal breast tissue that can predispose to sporadic breast cancer

  • First Published October 1, 2015
Perspective

The first five years of single-cell cancer genomics and beyond

  • First Published October 1, 2015
Perspective

The Mendelian disorders of the epigenetic machinery

  • First Published October 1, 2015
Perspective

Epigenomics and the structure of the living genome

  • First Published October 1, 2015
Perspective

Genomic approaches for understanding the genetics of complex disease

  • First Published October 1, 2015
Perspective

Enabling functional genomics with genome engineering

  • First Published October 1, 2015
Perspective

Biological data sciences in genome research

  • First Published October 1, 2015
Perspective

Linking RNA biology to lncRNAs

  • First Published October 1, 2015
Perspective

Parlez-vous VUS?

  • First Published October 1, 2015
Perspective

A vision for ubiquitous sequencing

  • First Published October 1, 2015
Perspective

Functional genomics bridges the gap between quantitative genetics and molecular biology

  • First Published October 1, 2015
Preface

Genome Research" > 20 Years of Genome Research

  • First Published October 1, 2015
Method

Enhanced virome sequencing using targeted sequence capture

  • First Published September 22, 2015
Research

Bacterial infection remodels the DNA methylation landscape of human dendritic cells

  • First Published September 21, 2015
Research

Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background

  • First Published September 16, 2015
Resource

Chlorocebus aethiops sabaeus)" > The genome of the vervet (Chlorocebus aethiops sabaeus)

  • First Published September 16, 2015
Research

Prepatterning of differentiation-driven nuclear lamin A/C-associated chromatin domains by GlcNAcylated histone H2B

  • First Published September 10, 2015
Research

Replication timing is regulated by the number of MCMs loaded at origins

  • First Published September 10, 2015
Research

Noise in gene expression is coupled to growth rate

  • First Published September 9, 2015
Research

Ficedula flycatchers" > Linked selection and recombination rate variation drive the evolution of the genomic landscape of differentiation across the speciation continuum of Ficedula flycatchers

  • First Published September 9, 2015
Method

CETCh-seq: CRISPR epitope tagging ChIP-seq of DNA-binding proteins

  • First Published September 9, 2015
Research

Ribosome profiling reveals an important role for translational control in circadian gene expression

  • First Published September 3, 2015
Research

Drosophila zygotic genome activation" > Zelda overcomes the high intrinsic nucleosome barrier at enhancers during Drosophila zygotic genome activation

  • First Published September 2, 2015
Research

Drosophila embryo" > Zelda is differentially required for chromatin accessibility, transcription factor binding, and gene expression in the early Drosophila embryo

  • First Published September 2, 2015
Research

DNA-guided establishment of nucleosome patterns within coding regions of a eukaryotic genome

  • First Published September 1, 2015
Corrigendum

Corrigendum: Unraveling determinants of transcription factor binding outside the core binding site

  • First Published September 1, 2015
Corrigendum

Corrigendum: Extensive microRNA-mediated crosstalk between lncRNAs and mRNAs in mouse embryonic stem cells

  • First Published September 1, 2015
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