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A comprehensive analysis of 3′ end sequencing data sets reveals novel polyadenylation signals and the repressive role of heterogeneous ribonucleoprotein C on cleavage and polyadenylation

  • First Published July 5, 2016
Corrigendum

Corrigendum: Divergence of a conserved elongation factor and transcription regulation in budding and fission yeast

  • First Published July 1, 2016
Resource

Diverse alternative back-splicing and alternative splicing landscape of circular RNAs

  • First Published June 30, 2016
Research

Transposons passively and actively contribute to evolution of the two-speed genome of a fungal pathogen

  • First Published June 20, 2016
Research

TBR1 regulates autism risk genes in the developing neocortex

  • First Published June 20, 2016
Method

Heterogeneity of transcription factor binding specificity models within and across cell lines

  • First Published June 16, 2016
Research

High-throughput functional comparison of promoter and enhancer activities

  • First Published June 16, 2016
Method

Dictyostelium" > Gene discovery by chemical mutagenesis and whole-genome sequencing in Dictyostelium

  • First Published June 15, 2016
Method

Multikernel linear mixed models for complex phenotype prediction

  • First Published June 14, 2016
Method

TransRate: reference-free quality assessment of de novo transcriptome assemblies

  • First Published June 1, 2016
Research

Reconstruction of ancestral chromosome architecture and gene repertoire reveals principles of genome evolution in a model yeast genus

  • First Published May 31, 2016
Research

Chromatin dynamics during DNA replication

  • First Published May 25, 2016
Research

Arabidopsis thaliana at single-gene resolution" > Genome-wide analysis of chromatin packing in Arabidopsis thaliana at single-gene resolution

  • First Published May 25, 2016
Research

Global analysis of transcriptionally engaged yeast RNA polymerase III reveals extended tRNA transcripts

  • First Published May 20, 2016
Method

Control of fluxes in metabolic networks

  • First Published May 19, 2016
Research

Selection and explosive growth alter genetic architecture and hamper the detection of causal rare variants

  • First Published May 18, 2016
Research

Specific down-regulation of spermatogenesis genes targeted by 22G RNAs in hybrid sterile males associated with an X-Chromosome introgression

  • First Published May 18, 2016
Research

Multiplex enhancer-reporter assays uncover unsophisticated TP53 enhancer logic

  • First Published May 18, 2016
Research

Divergence of a conserved elongation factor and transcription regulation in budding and fission yeast

  • First Published May 12, 2016
Research

A hot L1 retrotransposon evades somatic repression and initiates human colorectal cancer

  • First Published May 10, 2016
Method

Quantitative insertion-site sequencing (QIseq) for high throughput phenotyping of transposon mutants

  • First Published May 10, 2016
Research

The interaction of PRC2 with RNA or chromatin is mutually antagonistic

  • First Published May 9, 2016
Research

A novel nuclear genetic code alteration in yeasts and the evolution of codon reassignment in eukaryotes

  • First Published May 6, 2016
Research

Venus flytrap carnivorous lifestyle builds on herbivore defense strategies

  • First Published May 4, 2016
Method

Basset: learning the regulatory code of the accessible genome with deep convolutional neural networks

  • First Published May 3, 2016
Research

Distinct transcription factor complexes act on a permissive chromatin landscape to establish regionalized gene expression in CNS stem cells

  • First Published May 2, 2016
Resource

Improved definition of the mouse transcriptome via targeted RNA sequencing

  • First Published May 2, 2016
Corrigendum

Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

  • First Published May 2, 2016
Corrigendum

Corrigendum: Model-based analyses of whole-genome data reveal a complex evolutionary history involving archaic introgression in Central African Pygmies

  • First Published May 2, 2016
Resource

The mRNA-bound proteome of the early fly embryo

  • First Published April 28, 2016
Resource

Identification of the long, edited dsRNAome of LPS-stimulated immune cells

  • First Published April 21, 2016
Research

Impact of the X Chromosome and sex on regulatory variation

  • First Published April 21, 2016
Method

SMASH, a fragmentation and sequencing method for genomic copy number analysis

  • First Published April 14, 2016
Research

Evolutionary assembly patterns of prokaryotic genomes

  • First Published April 14, 2016
Research

Large-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networks

  • First Published April 13, 2016
Research

Drosophila" > Evidence for the fixation of gene duplications by positive selection in Drosophila

  • First Published April 12, 2016
Research

Zygotes segregate entire parental genomes in distinct blastomere lineages causing cleavage-stage chimerism and mixoploidy

  • First Published April 12, 2016
Research

Clustered mutations in hominid genome evolution are consistent with APOBEC3G enzymatic activity

  • First Published April 7, 2016
Research

Three-dimensional disorganization of the cancer genome occurs coincident with long-range genetic and epigenetic alterations

  • First Published April 6, 2016
Research

Sperm is epigenetically programmed to regulate gene transcription in embryos

  • First Published March 31, 2016
Method

Sequence-targeted nucleosome sliding in vivo by a hybrid Chd1 chromatin remodeler

  • First Published March 18, 2016
Research

nanoCAGE reveals 5′ UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs

  • First Published March 16, 2016
Method

An extended set of yeast-based functional assays accurately identifies human disease mutations

  • First Published March 14, 2016
Research

Comprehensive benchmarking reveals H2BK20 acetylation as a distinctive signature of cell-state-specific enhancers and promoters

  • First Published March 8, 2016
Method

2C-Cas9: a versatile tool for clonal analysis of gene function

  • First Published March 8, 2016
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