Your search for returned 6,372 results
Research
The role of insulators and transcription in 3D chromatin organization of flies
- First Published March 30, 2022
Research
A hidden layer of structural variation in transposable elements reveals potential genetic modifiers in human disease-risk loci
- First Published March 24, 2022
Method
Classification and clustering of RNA crosslink-ligation data reveal complex structures and homodimers
- First Published March 24, 2022
Method
A general framework for identifying oligogenic combinations of rare variants in complex disorders
- First Published March 17, 2022
Method
A general calculus of fitness landscapes finds genes under selection in cancers
- First Published March 17, 2022
Method
Sequencing of individual barcoded cDNAs using Pacific Biosciences and Oxford Nanopore Technologies reveals platform-specific error patterns
- First Published March 17, 2022
Research
Genome-wide transcript and protein analysis highlights the role of protein homeostasis in the aging mouse heart
- First Published March 11, 2022
Research
Paramecium" > GC content, but not nucleosome positioning, directly contributes to intron splicing efficiency in Paramecium
- First Published March 9, 2022
Research
Paramecium macronuclear genome" > Broad domains of histone marks in the highly compact Paramecium macronuclear genome
- First Published March 9, 2022
Method
Pan-human consensus genome significantly improves the accuracy of RNA-seq analyses
- First Published March 7, 2022
Method
An association test of the spatial distribution of rare missense variants within protein structures identifies Alzheimer's disease–related patterns
- First Published February 24, 2022
Method
Discovery of an unusually high number of de novo mutations in sperm of older men using duplex sequencing
- First Published February 24, 2022
Method
Identification of phenotype-specific networks from paired gene expression–cell shape imaging data
- First Published February 23, 2022
Method
A framework to score the effects of structural variants in health and disease
- First Published February 23, 2022
Method
Low-input RNase footprinting for simultaneous quantification of cytosolic and mitochondrial translation
- First Published February 22, 2022
Research
Functional noncoding SNPs in human endothelial cells fine-map vascular trait associations
- First Published February 22, 2022
Research
Somatic structural variant formation is guided by and influences genome architecture
- First Published February 17, 2022
Research
Accumulation and ineffective silencing of transposable elements on an avian W Chromosome
- First Published February 11, 2022
Research
Whole-genome resequencing of temporally stratified samples reveals substantial loss of haplotype diversity in the highly inbred Scandinavian wolf population
- First Published February 8, 2022
Method
NicE-C efficiently reveals open chromatin–associated chromosome interactions at high resolution
- First Published February 1, 2022
Research
Mendelian randomization analyses implicate biogenesis of translation machinery in human aging
- First Published January 25, 2022
Research
Joint actions of diverse transcription factor families establish neuron-type identities and promote enhancer selectivity
- First Published January 24, 2022
Resource
Mitochondrial DNA variation across 56,434 individuals in gnomAD
- First Published January 24, 2022
Research
Distal regulation, silencers, and a shared combinatorial syntax are hallmarks of animal embryogenesis
- First Published January 19, 2022
Method
Domain-adaptive neural networks improve cross-species prediction of transcription factor binding
- First Published January 18, 2022
Research
Characterization of transcript enrichment and detection bias in single-nucleus RNA-seq for mapping of distinct human adipocyte lineages
- First Published January 18, 2022
Method
Accurate and robust inference of microbial growth dynamics from metagenomic sequencing reveals personalized growth rates
- First Published January 5, 2022
Resource
Zebrafish transposable elements show extensive diversification in age, genomic distribution, and developmental expression
- First Published January 5, 2022
Review
Advancing genomic technologies and clinical awareness accelerates discovery of disease-associated tandem repeat sequences
- First Published December 29, 2021
Method
Antibody-free profiling of transcription factor occupancy during early embryogenesis by FitCUT&RUN
- First Published December 29, 2021
Resource
Anopheles coluzzii" > Transposable element variants and their potential adaptive impact in urban populations of the malaria vector Anopheles coluzzii
- First Published December 29, 2021
Research
Meta-analysis of human and mouse ALS astrocytes reveals multi-omic signatures of inflammatory reactive states
- First Published December 28, 2021
Research
Low-frequency somatic copy number alterations in normal human lymphocytes revealed by large-scale single-cell whole-genome profiling
- First Published December 28, 2021
Research
Spatial organization of chromosomes leads to heterogeneous chromatin motion and drives the liquid- or gel-like dynamical behavior of chromatin
- First Published December 28, 2021
Method
A full-proteome, interaction-specific characterization of mutational hotspots across human cancers
- First Published December 28, 2021