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Letter

Functional diversity for REST (NRSF) is defined by in vivo binding affinity hierarchies at the DNA sequence level

  • First Published April 28, 2009
Letter

SMAD7 expression" > The colorectal cancer risk at 18q21 is caused by a novel variant altering SMAD7 expression

  • First Published April 24, 2009
Next-Generation DNA Sequencing/Review

Microbial community profiling for human microbiome projects: Tools, techniques, and challenges

  • First Published April 21, 2009
Resource

High resolution mapping of expression QTLs in heterogeneous stock mice in multiple tissues

  • First Published April 17, 2009
Letter

Comparative inference of illegitimate recombination between rice and sorghum duplicated genes produced by polyploidization

  • First Published April 16, 2009
Letter

Dynamic reprogramming of transcription factors to and from the subtelomere

  • First Published April 16, 2009
Letter

The origins of apicomplexan sequence innovation

  • First Published April 10, 2009
Letter

Streptococcus pneumoniae mutants reveals novel mechanisms of resistance" > Genome sequencing of linezolid-resistant Streptococcus pneumoniae mutants reveals novel mechanisms of resistance

  • First Published April 6, 2009
Letter

Breakpoint regions and homologous synteny blocks in chromosomes have different evolutionary histories

  • First Published April 2, 2009
Errata

Erratum

  • First Published April 1, 2009
Next-Generation DNA Sequencing/Review

Next-generation DNA sequencing of paired-end tags (PET) for transcriptome and genome analyses

  • First Published April 1, 2009
Letter

New class of microRNA targets containing simultaneous 5′-UTR and 3′-UTR interaction sites

  • First Published March 31, 2009
Letter

Signals of recent positive selection in a worldwide sample of human populations

  • First Published March 23, 2009
Letter

Darwinian and demographic forces affecting human protein coding genes

  • First Published March 11, 2009
Methods

Distinct DNA methylation patterns characterize differentiated human embryonic stem cells and developing human fetal liver

  • First Published March 9, 2009
Next-Generation DNA Sequencing/Review

Finding the fifth base: Genome-wide sequencing of cytosine methylation

  • First Published March 9, 2009
Letter

Acidothermus cellulolyticus 11B provides insights into its ecophysiological and evolutionary adaptations" > Complete genome of the cellulolytic thermophile Acidothermus cellulolyticus 11B provides insights into its ecophysiological and evolutionary adaptations

  • First Published March 6, 2009
Letter

Geographical structure and differential natural selection among North European populations

  • First Published March 5, 2009
Methods

Integrating siRNA and protein–protein interaction data to identify an expanded insulin signaling network

  • First Published March 4, 2009
Letter

Mosaic retroposon insertion patterns in placental mammals

  • First Published March 4, 2009
Erratum

Genomic copy number determination in cancer cells from single nucleotide polymorphism microarrays based on quantitative genotyping corrected for aneuploidy

  • First Published March 2, 2009
Letter

Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns

  • First Published February 27, 2009
Resource

ABySS: A parallel assembler for short read sequence data

  • First Published February 27, 2009
Letter

Drosophila genus" > General gene movement off the X chromosome in the Drosophila genus

  • First Published February 27, 2009
Letter

Global diversity in the human salivary microbiome

  • First Published February 27, 2009
Letter

Comparative analysis of H2A.Z nucleosome organization in the human and yeast genomes

  • First Published February 26, 2009
Resource

Exploring the human genome with functional maps

  • First Published February 26, 2009
Resource

Global networks of functional coupling in eukaryotes from comprehensive data integration

  • First Published February 25, 2009
Methods

Single-pass classification of all noncoding sequences in a bacterial genome using phylogenetic profiles

  • First Published February 23, 2009
Letter

Genomic mapping of binding regions for the Ecdysone receptor protein complex

  • First Published February 23, 2009
Letter

The impact of genomic neighborhood on the evolution of human and chimpanzee transcriptome

  • First Published February 19, 2009
Methods

Dissecting transcription regulatory pathways through a new bacterial one-hybrid reporter system

  • First Published February 18, 2009
Letter

Hox gene clusters of the green anole lizard" > Atypical relaxation of structural constraints in Hox gene clusters of the green anole lizard

  • First Published February 18, 2009
Resource

HistoneHits: A database for histone mutations and their phenotypes

  • First Published February 13, 2009
Letter

Global distribution of genomic diversity underscores rich complex history of continental human populations

  • First Published February 13, 2009
Resource

Breakpoint graphs and ancestral genome reconstructions

  • First Published February 13, 2009
Letter

Alternative splicing of anciently exonized 5S rRNA regulates plant transcription factor TFIIIA

  • First Published February 10, 2009
Letter

mtDNA mutation pattern in tumors and human evolution are shaped by similar selective constraints

  • First Published February 10, 2009
Letter

The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer

  • First Published February 10, 2009
Methods

Detecting heterozygosity in shotgun genome assemblies: Lessons from obligately outcrossing nematodes

  • First Published February 9, 2009
Letter

Histone H3.3 incorporation provides a unique and functionally essential telomeric chromatin in embryonic stem cells

  • First Published February 5, 2009
Letter

Anopheles funestus, a major malaria vector" > Two duplicated P450 genes are associated with pyrethroid resistance in Anopheles funestus, a major malaria vector

  • First Published February 5, 2009
Letter

Callorhinchus milii" > Into the blue: Gene duplication and loss underlie color vision adaptations in a deep-sea chimaera, the elephant shark Callorhinchus milii

  • First Published February 4, 2009
Letter

Common polymorphic transcript variation in human disease

  • First Published February 2, 2009
Resource

C. elegans" > Massively parallel sequencing of the polyadenylated transcriptome of C. elegans

  • First Published January 30, 2009
Letter

The functional importance of telomere clustering: Global changes in gene expression result from SIR factor dispersion

  • First Published January 29, 2009
Resource

Multiple whole-genome alignments without a reference organism

  • First Published January 28, 2009
Article

High-resolution DNA-binding specificity analysis of yeast transcription factors

  • First Published January 21, 2009
Letter

HapMap methylation-associated SNPs, markers of germline DNA methylation, positively correlate with regional levels of human meiotic recombination

  • First Published January 21, 2009
Letter

Saccharomyces cerevisiae as revealed by whole-genome resequencing" > Repetitive sequence variation and dynamics in the ribosomal DNA array of Saccharomyces cerevisiae as revealed by whole-genome resequencing

  • First Published January 13, 2009
Article

Human gamma-satellite DNA maintains open chromatin structure and protects a transgene from epigenetic silencing

  • First Published January 13, 2009
Methods

A transcription factor affinity-based code for mammalian transcription initiation

  • First Published January 13, 2009
Methods

Genomic copy number determination in cancer cells from single nucleotide polymorphism microarrays based on quantitative genotyping corrected for aneuploidy

  • First Published January 13, 2009
LETTER

Thylacinus cynocephalus)" > The mitochondrial genome sequence of the Tasmanian tiger (Thylacinus cynocephalus)

  • First Published January 12, 2009
Resource

The genomic architecture of segmental duplications and associated copy number variants in dogs

  • First Published January 7, 2009
Letter

Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers

  • First Published January 7, 2009
Letter

Splicing factor SFRS1 recognizes a functionally diverse landscape of RNA transcripts

  • First Published December 30, 2008
Letter

Neurospora crassa" > Relics of repeat-induced point mutation direct heterochromatin formation in Neurospora crassa

  • First Published December 17, 2008
Resource

MicroRNA target prediction by expression analysis of host genes

  • First Published December 16, 2008
Resource

A high-density SNP-based linkage map of the chicken genome reveals sequence features correlated with recombination rate

  • First Published December 16, 2008
Methods

Genome-wide profiling of salt fractions maps physical properties of chromatin

  • First Published December 16, 2008
Methods

Genome-wide detection and analysis of hippocampus core promoters using DeepCAGE

  • First Published December 11, 2008
Letter

HBEGF, SRA1, and IK: Three cosegregating genes as determinants of cardiomyopathy" > HBEGF, SRA1, and IK: Three cosegregating genes as determinants of cardiomyopathy

  • First Published December 8, 2008
RESOURCE

De novo fragment assembly with short mate-paired reads: Does the read length matter?

  • First Published December 3, 2008
LETTER

A sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genome

  • First Published December 3, 2008
LETTER

Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains

  • First Published December 3, 2008
ARTICLE

Pseudomonas aeruginosa" > Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool Epidemic Strain of Pseudomonas aeruginosa

  • First Published December 1, 2008
LETTER

H3K27me3 forms BLOCs over silent genes and intergenic regions and specifies a histone banding pattern on a mouse autosomal chromosome

  • First Published December 1, 2008
LETTER

Identification of miniature inverted-repeat transposable elements (MITEs) and biogenesis of their siRNAs in the Solanaceae: New functional implications for MITEs

  • First Published November 26, 2008
RESOURCE

Dissecting the effects of mtDNA variations on complex traits using mouse conplastic strains

  • First Published November 26, 2008
Methods

MSB: A mean-shift-based approach for the analysis of structural variation in the genome

  • First Published November 26, 2008
RESOURCE

Fast and flexible simulation of DNA sequence data

  • First Published November 24, 2008
LETTER

Sequencing human–gibbon breakpoints of synteny reveals mosaic new insertions at rearrangement sites

  • First Published November 24, 2008
RESOURCE

EnsemblCompara GeneTrees: Complete, duplication-aware phylogenetic trees in vertebrates

  • First Published November 24, 2008
LETTER

Natural selection on gene function drives the evolution of LTR retrotransposon families in the rice genome

  • First Published November 24, 2008
Methods

Inferring genomic flux in bacteria

  • First Published November 17, 2008
Methods

Pseudomonas syringae pv. oryzae" > De novo assembly using low-coverage short read sequence data from the rice pathogen Pseudomonas syringae pv. oryzae

  • First Published November 17, 2008
Resource

Mapping DNA structural variation in dogs

  • First Published November 17, 2008
Methods

A SILAC-based DNA protein interaction screen that identifies candidate binding proteins to functional DNA elements

  • First Published November 17, 2008
LETTER

Chromosomal instability mediated by non-B DNA: Cruciform conformation and not DNA sequence is responsible for recurrent translocation in humans

  • First Published November 7, 2008
ARTICLE

Allele-specific gene expression patterns in primary leukemic cells reveal regulation of gene expression by CpG site methylation

  • First Published November 7, 2008
LETTER

Arabidopsis differentiation and stress responses" > Novel long non-protein coding RNAs involved in Arabidopsis differentiation and stress responses

  • First Published November 7, 2008
Methods

High-resolution human core-promoter prediction with CoreBoost_HM

  • First Published November 7, 2008
LETTER

Widespread balancing selection and pathogen-driven selection at blood group antigen genes

  • First Published November 7, 2008
RESOURCE

Caenorhabditis elegans microRNA promoter activity" > Genome-scale spatiotemporal analysis of Caenorhabditis elegans microRNA promoter activity

  • First Published November 3, 2008
LETTER

Characterization of the bovine pseudoautosomal boundary: Documenting the evolutionary history of mammalian sex chromosomes

  • First Published November 3, 2008
Methods

Hox cis-regulatory elements" > Multigenome DNA sequence conservation identifies Hox cis-regulatory elements

  • First Published November 3, 2008
ERRATUM

Erratum

  • First Published October 30, 2008
REVIEW

Defensins and the dynamic genome: What we can learn from structural variation at human chromosome band 8p23.1

  • First Published October 30, 2008
LETTER

Oryza sativa" > Genome-wide identification and analysis of small RNAs originated from natural antisense transcripts in Oryza sativa

  • First Published October 29, 2008
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