Your search for returned 6,373 results
Research
Somatic rearrangements across cancer reveal classes of samples with distinct patterns of DNA breakage and rearrangement-induced hypermutability
- First Published November 2, 2012
Research
Stabilization of the promoter nucleosomes in nucleosome-free regions by the yeast Cyc8–Tup1 corepressor
- First Published November 2, 2012
Research
Autozygome-guided exome sequencing in retinal dystrophy patients reveals pathogenetic mutations and novel candidate disease genes
- First Published October 26, 2012
Research
CpG islands and GC content dictate nucleosome depletion in a transcription-independent manner at mammalian promoters
- First Published October 25, 2012
Method
Modeling kinetic rate variation in third generation DNA sequencing data to detect putative modifications to DNA bases
- First Published October 23, 2012
Research
Pluripotent stem cells escape from senescence-associated DNA methylation changes
- First Published October 18, 2012
Research
Comparative motif discovery combined with comparative transcriptomics yields accurate targetome and enhancer predictions
- First Published October 15, 2012
Research
Differentially expressed, variant U1 snRNAs regulate gene expression in human cells
- First Published October 15, 2012
Research
Nurture trumps nature in a longitudinal survey of salivary bacterial communities in twins from early adolescence to early adulthood
- First Published October 12, 2012
Method
Sequencing the unsequenceable: Expanded CGG-repeat alleles of the fragile X gene
- First Published October 11, 2012
Research
LRRC37 gene family" > Evolutionary dynamism of the primate LRRC37 gene family
- First Published October 11, 2012
Method
Linking the signaling cascades and dynamic regulatory networks controlling stress responses
- First Published October 11, 2012
Method
SeqFold: Genome-scale reconstruction of RNA secondary structure integrating high-throughput sequencing data
- First Published October 11, 2012
Research
Drosophila mauritiana" > Genome-wide patterns of natural variation reveal strong selective sweeps and ongoing genomic conflict in Drosophila mauritiana
- First Published October 10, 2012
Method
PUB-NChIP—“in vivo biotinylation” approach to study chromatin in proximity to a protein of interest
- First Published October 4, 2012
Resource
A calibrated human Y-chromosomal phylogeny based on resequencing
- First Published October 4, 2012
Perspective
Genetic basis of kidney cancer: Role of genomics for the development of disease-based therapeutics
- First Published October 4, 2012
Research
Small noncoding differentially methylated copy-number variants, including lncRNA genes, cause a lethal lung developmental disorder
- First Published October 3, 2012
Research
Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events
- First Published October 2, 2012
Method
Spatiotemporal clustering of the epigenome reveals rules of dynamic gene regulation
- First Published October 2, 2012
Method
Haplotype-based profiling of subtle allelic imbalance with SNP arrays
- First Published October 1, 2012
Research
Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer
- First Published October 1, 2012
Perspective
Translating genomic information into clinical medicine: Lung cancer as a paradigm
- First Published September 27, 2012
Method
Integration of ChIP-seq and machine learning reveals enhancers and a predictive regulatory sequence vocabulary in melanocytes
- First Published September 27, 2012
Research
Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner
- First Published September 26, 2012
Method
Efficient targeted mutagenesis in the monarch butterfly using zinc-finger nucleases
- First Published September 25, 2012
Method
P-value-based regulatory motif discovery using positional weight matrices" > P-value-based regulatory motif discovery using positional weight matrices
- First Published September 18, 2012
Research
Computational analysis and characterization of UCE-like elements (ULEs) in plant genomes
- First Published September 17, 2012
Research
The transcriptional landscape and mutational profile of lung adenocarcinoma
- First Published September 13, 2012
Resource
SOAPindel: Efficient identification of indels from short paired reads
- First Published September 12, 2012
Research
Extensive somatic L1 retrotransposition in colorectal tumors
- First Published September 11, 2012
Research
Modeling of epigenome dynamics identifies transcription factors that mediate Polycomb targeting
- First Published September 10, 2012
Method
Genome-wide mapping of nucleosome positioning and DNA methylation within individual DNA molecules
- First Published September 7, 2012
Method
Spark: A navigational paradigm for genomic data exploration
- First Published September 7, 2012
Resource
Xenopus tropicalis transcriptome over development" > RNA sequencing reveals a diverse and dynamic repertoire of the Xenopus tropicalis transcriptome over development
- First Published September 7, 2012
Research
Dynamic landscape of tandem 3′ UTRs during zebrafish development
- First Published September 5, 2012
Resource
Annotation of functional variation in personal genomes using RegulomeDB
- First Published September 5, 2012
Resource
Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors
- First Published September 5, 2012
Research
Widespread plasticity in CTCF occupancy linked to DNA methylation
- First Published September 5, 2012
Method
Ubiquitous heterogeneity and asymmetry of the chromatin environment at regulatory elements
- First Published September 5, 2012
Method
Predicting cell-type–specific gene expression from regions of open chromatin
- First Published September 5, 2012
Method
Combining RT-PCR-seq and RNA-seq to catalog all genic elements encoded in the human genome
- First Published September 5, 2012
Resource
GENCODE: The reference human genome annotation for The ENCODE Project
- First Published September 5, 2012
Method
Sequence and chromatin determinants of cell-type–specific transcription factor binding
- First Published September 5, 2012
Research
A highly integrated and complex PPARGC1A transcription factor binding network in HepG2 cells
- First Published September 5, 2012
Research
Discovery of hundreds of mirtrons in mouse and human small RNA data
- First Published September 5, 2012
Research
Understanding transcriptional regulation by integrative analysis of transcription factor binding data
- First Published September 5, 2012
Research
Long noncoding RNAs are rarely translated in two human cell lines
- First Published September 5, 2012
Resource
ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia
- First Published September 5, 2012
Method
Linking disease associations with regulatory information in the human genome
- First Published September 5, 2012
Resource
The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression
- First Published September 5, 2012
Research
Personal and population genomics of human regulatory variation
- First Published September 5, 2012
Research
Deep sequencing of subcellular RNA fractions shows splicing to be predominantly co-transcriptional in the human genome but inefficient for lncRNAs
- First Published September 5, 2012
Research
Copy number variation leads to considerable diversity for B but not A haplotypes of the human KIR genes encoding NK cell receptors
- First Published September 4, 2012
Research
Spreading of X chromosome inactivation via a hierarchy of defined Polycomb stations
- First Published September 4, 2012
Research
Time series community genomics analysis reveals rapid shifts in bacterial species, strains, and phage during infant gut colonization
- First Published August 30, 2012
Method
High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression
- First Published August 30, 2012
Research
Guthrie card methylomics identifies temporally stable epialleles that are present at birth in humans
- First Published August 23, 2012
Research
cis-trans regulation in the evolution of mouse gene expression" > Extensive compensatory cis-trans regulation in the evolution of mouse gene expression
- First Published August 23, 2012
Research
IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation" > A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation
- First Published August 16, 2012
Research
Drosophila species" > The BEAF-32 insulator coordinates genome organization and function during the evolution of Drosophila species
- First Published August 15, 2012
Resource
A comprehensive molecular cytogenetic analysis of chromosome rearrangements in gibbons
- First Published August 14, 2012
Research
Genome-wide search for novel human uORFs and N-terminal protein extensions using ribosomal footprinting
- First Published August 9, 2012
Method
Copy-number-aware differential analysis of quantitative DNA sequencing data
- First Published August 9, 2012
Research
Positionally biased gene loss after whole genome duplication: Evidence from human, yeast, and plant
- First Published July 26, 2012
Resource
A fine scale phenotype–genotype virulence map of a bacterial pathogen
- First Published July 23, 2012
Research
Microsporidian genome analysis reveals evolutionary strategies for obligate intracellular growth
- First Published July 18, 2012
Resource
Incorporating RNA-seq data into the zebrafish Ensembl genebuild
- First Published July 12, 2012
Research
cis-regulatory modules" > Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules
- First Published July 10, 2012
Resource
C. briggsae transcriptome" > RNA-seq analysis of the C. briggsae transcriptome
- First Published July 6, 2012
Method
Ultrafast genome-wide scan for SNP–SNP interactions in common complex disease
- First Published July 5, 2012
Research
Drosophila genome" > Nature and function of insulator protein binding sites in the Drosophila genome
- First Published July 5, 2012
Research
Conservation of replication timing reveals global and local regulation of replication origin activity
- First Published July 5, 2012
Method
Systematic elucidation and in vivo validation of sequences enriched in hindbrain transcriptional control
- First Published July 3, 2012
Method
nFuse: Discovery of complex genomic rearrangements in cancer using high-throughput sequencing
- First Published June 28, 2012
Resource
A miRNA-regulatory network explains how dysregulated miRNAs perturb oncogenic processes across diverse cancers
- First Published June 28, 2012
Research
CRISPR targeting reveals a reservoir of common phages associated with the human gut microbiome
- First Published June 25, 2012
Research
Transcription factor redundancy and tissue-specific regulation: Evidence from functional and physical network connectivity
- First Published June 22, 2012