Your search for returned 6,372 results
Research
Sister chromatid telomere fusions, but not NHEJ-mediated inter-chromosomal telomere fusions, occur independently of DNA ligases 3 and 4
- First Published March 3, 2016
Research
Human MAF1 targets and represses active RNA polymerase III genes by preventing recruitment rather than inducing long-term transcriptional arrest
- First Published March 3, 2016
Method
A time- and cost-effective strategy to sequence mammalian Y Chromosomes: an application to the de novo assembly of gorilla Y
- First Published March 2, 2016
Research
Genome-wide A-to-I RNA editing in fungi independent of ADAR enzymes
- First Published March 2, 2016
Research
Callithrix jacchus genome" > Discovery of a new repeat family in the Callithrix jacchus genome
- First Published February 25, 2016
Research
Transmission of human mtDNA heteroplasmy in the Genome of the Netherlands families: support for a variable-size bottleneck
- First Published February 25, 2016
Method
Integrative subcellular proteomic analysis allows accurate prediction of human disease-causing genes
- First Published February 24, 2016
Research
Enhancer methylation dynamics contribute to cancer plasticity and patient mortality
- First Published February 23, 2016
Research
Neurospora tetrasperma" > Introgression maintains the genetic integrity of the mating-type determining chromosome of the fungus Neurospora tetrasperma
- First Published February 18, 2016
Research
Alternative splicing modulated by genetic variants demonstrates accelerated evolution regulated by highly conserved proteins
- First Published February 17, 2016
Research
Model-based analyses of whole-genome data reveal a complex evolutionary history involving archaic introgression in Central African Pygmies
- First Published February 17, 2016
Research
Great ape Y Chromosome and mitochondrial DNA phylogenies reflect subspecies structure and patterns of mating and dispersal
- First Published February 16, 2016
Method
A network-based analysis of colon cancer splicing changes reveals a tumorigenesis-favoring regulatory pathway emanating from ELK1
- First Published February 9, 2016
Method
Chromosome-scale shotgun assembly using an in vitro method for long-range linkage
- First Published February 4, 2016
Method
Degradation dynamics of microRNAs revealed by a novel pulse-chase approach
- First Published January 28, 2016
Method
A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening
- First Published January 26, 2016
Research
A-type lamins bind both hetero- and euchromatin, the latter being regulated by lamina-associated polypeptide 2 alpha
- First Published January 21, 2016
Method
Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq
- First Published January 19, 2016
Method
Assessment of megabase-scale somatic copy number variation using single-cell sequencing
- First Published January 15, 2016
Research
Pervasive polymorphic imprinted methylation in the human placenta
- First Published January 14, 2016
Research
APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replication
- First Published January 11, 2016
Research
Concerted activities of Mcm4, Sld3, and Dbf4 in control of origin activation and DNA replication fork progression
- First Published January 5, 2016
Research
The life history of retrocopies illuminates the evolution of new mammalian genes
- First Published January 4, 2016
Research
Indigenous Arabs are descendants of the earliest split from ancient Eurasian populations
- First Published January 4, 2016
Research
TP53 regulates miRNA association with AGO2 to remodel the miRNA–mRNA interaction network
- First Published December 23, 2015
Research
Worldwide patterns of genomic variation and admixture in gray wolves
- First Published December 17, 2015
Research
Nasonia" > DNA methylation changes induced by long and short photoperiods in Nasonia
- First Published December 15, 2015
Resource
Building a genomic framework for prospective MRSA surveillance in the United Kingdom and the Republic of Ireland
- First Published December 15, 2015
Resource
Ciona intestinalis" > Genome-wide identification and characterization of transcription start sites and promoters in the tunicate Ciona intestinalis
- First Published December 14, 2015
Method
metilene: fast and sensitive calling of differentially methylated regions from bisulfite sequencing data
- First Published December 2, 2015
Resource
H3ABioNet, a sustainable pan-African bioinformatics network for human heredity and health in Africa
- First Published December 1, 2015
Research
Genome-wide cooperation by HAT Gcn5, remodeler SWI/SNF, and chaperone Ydj1 in promoter nucleosome eviction and transcriptional activation
- First Published November 24, 2015
Research
EHMT2 directs DNA methylation for efficient gene silencing in mouse embryos
- First Published November 17, 2015
Method
cis-regulatory analysis in the mammalian central nervous system" > Massively parallel cis-regulatory analysis in the mammalian central nervous system
- First Published November 17, 2015
Research
SCRaMbLE generates designed combinatorial stochastic diversity in synthetic chromosomes
- First Published November 13, 2015
Resource
The pig X and Y Chromosomes: structure, sequence, and evolution
- First Published November 11, 2015
Research
The chromatin environment shapes DNA replication origin organization and defines origin classes
- First Published November 11, 2015
Method
INTEGRATE: gene fusion discovery using whole genome and transcriptome data
- First Published November 10, 2015
Research
Subcellular RNA profiling links splicing and nuclear DICER1 to alternative cleavage and polyadenylation
- First Published November 6, 2015
Research
Loss of HP1 causes depletion of H3K27me3 from facultative heterochromatin and gain of H3K27me2 at constitutive heterochromatin
- First Published November 4, 2015
Research
Nascent RNA folding mitigates transcription-associated mutagenesis
- First Published October 30, 2015
Research
Tribolium castaneum" > MicroRNA evolution, expression, and function during short germband development in Tribolium castaneum
- First Published October 30, 2015
Research
Daphnia pulex" > High mutational rates of large-scale duplication and deletion in Daphnia pulex
- First Published October 30, 2015
Research
Phylogenomic evidence for ancient hybridization in the genomes of living cats (Felidae)
- First Published October 30, 2015
Research
Active chromatin and transcription play a key role in chromosome partitioning into topologically associating domains
- First Published October 30, 2015
Research
CAGE profiling of ncRNAs in hepatocellular carcinoma reveals widespread activation of retroviral LTR promoters in virus-induced tumors
- First Published October 28, 2015
Research
Ribosome profiling reveals the rhythmic liver translatome and circadian clock regulation by upstream open reading frames
- First Published October 20, 2015
Research
Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/ enhancer-binding protein beta binding sites
- First Published October 20, 2015
Method
A probabilistic method for testing and estimating selection differences between populations
- First Published October 13, 2015
Research
An extended family of novel vertebrate photopigments is widely expressed and displays a diversity of function
- First Published October 8, 2015
Method
Oxford Nanopore sequencing, hybrid error correction, and de novo assembly of a eukaryotic genome
- First Published October 7, 2015
Research
Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells
- First Published October 1, 2015
Perspective
The path to routine use of genomic biomarkers in the cancer clinic
- First Published October 1, 2015
Perspective
The intersection of microbiome and host at the skin interface: genomic- and metagenomic-based insights
- First Published October 1, 2015
Perspective
Defining cell types and states with single-cell genomics
- First Published October 1, 2015
Research
Signatures of post-zygotic structural genetic aberrations in the cells of histologically normal breast tissue that can predispose to sporadic breast cancer
- First Published October 1, 2015
Perspective
The first five years of single-cell cancer genomics and beyond
- First Published October 1, 2015
Perspective
Genomic approaches for understanding the genetics of complex disease
- First Published October 1, 2015
Perspective
Functional genomics bridges the gap between quantitative genetics and molecular biology
- First Published October 1, 2015
Perspective
Half dozen of one, six billion of the other: What can small- and large-scale molecular systems biology learn from one another?
- First Published October 1, 2015
Method
Enhanced virome sequencing using targeted sequence capture
- First Published September 22, 2015
Research
Bacterial infection remodels the DNA methylation landscape of human dendritic cells
- First Published September 21, 2015
Research
Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background
- First Published September 16, 2015
Resource
Chlorocebus aethiops sabaeus)" > The genome of the vervet (Chlorocebus aethiops sabaeus)
- First Published September 16, 2015
Research
Prepatterning of differentiation-driven nuclear lamin A/C-associated chromatin domains by GlcNAcylated histone H2B
- First Published September 10, 2015
Research
Replication timing is regulated by the number of MCMs loaded at origins
- First Published September 10, 2015
Research
SORBS2 transcription is activated by telomere position effect–over long distance upon telomere shortening in muscle cells from patients with facioscapulohumeral dystrophy" > SORBS2 transcription is activated by telomere position effect–over long distance upon telomere shortening in muscle cells from patients with facioscapulohumeral dystrophy
- First Published September 10, 2015
Method
CETCh-seq: CRISPR epitope tagging ChIP-seq of DNA-binding proteins
- First Published September 9, 2015
Research
Ribosome profiling reveals an important role for translational control in circadian gene expression
- First Published September 3, 2015
Research
Drosophila zygotic genome activation" > Zelda overcomes the high intrinsic nucleosome barrier at enhancers during Drosophila zygotic genome activation
- First Published September 2, 2015
Research
Drosophila embryo" > Zelda is differentially required for chromatin accessibility, transcription factor binding, and gene expression in the early Drosophila embryo
- First Published September 2, 2015
Research
DNA-guided establishment of nucleosome patterns within coding regions of a eukaryotic genome
- First Published September 1, 2015
Corrigendum
Corrigendum: Unraveling determinants of transcription factor binding outside the core binding site
- First Published September 1, 2015
Corrigendum
Corrigendum: Extensive microRNA-mediated crosstalk between lncRNAs and mRNAs in mouse embryonic stem cells
- First Published September 1, 2015
Method
Structured nucleosome fingerprints enable high-resolution mapping of chromatin architecture within regulatory regions
- First Published August 27, 2015
Research
Integrative analysis of RNA, translation, and protein levels reveals distinct regulatory variation across humans
- First Published August 21, 2015
Resource
Drosophila by 56 RNA binding proteins" > Regulation of alternative splicing in Drosophila by 56 RNA binding proteins
- First Published August 20, 2015
Research
DIS3 shapes the RNA polymerase II transcriptome in humans by degrading a variety of unwanted transcripts
- First Published August 20, 2015