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Research

Analysis of a cell-free DNA–based cancer screening cohort links fragmentomic profiles, nuclease levels, and plasma DNA concentrations

Yasine Malki
Guannan Kang
W.K. Jacky Lam
Qing Zhou
Suk Hang Cheng
Peter P.H. Cheung Jinyue Bai Ming Lok Chan Chui Ting Lee Wenlei Peng Yiqiong Zhang Wanxia Gai Winsome W.S. Wong Mary-Jane L. Ma Wenshuo Li Xinzhou Xu Zhuoran Gao Irene O.L. Tse Huimin Shang
... [+14 authors] ...,
L.Y. Lois Choy
Peiyong Jiang
K.C. Allen Chan
Y.M. Dennis Lo

First Published November 27, 2024

Research

Genomic origin, fragmentomics, and transcriptional properties of long cell-free DNA molecules in human plasma

Huiwen Che
Peiyong Jiang
L.Y. Lois Choy
Suk Hang Cheng
Wenlei Peng
Rebecca W.Y. Chan Jing Liu Qing Zhou W.K. Jacky Lam Stephanie C.Y. Yu So Ling Lau Tak Y. Leung John Wong Vincent Wai-Sun Wong
... [+9 authors] ...,
Grace L.H. Wong
Stephen L. Chan
K.C. Allen Chan
Y.M. Dennis Lo

First Published February 26, 2024

Method

Detection and characterization of jagged ends of double-stranded DNA in plasma

Peiyong Jiang
Tingting Xie
Spencer C. Ding
Ze Zhou
Suk Hang Cheng
Rebecca W.Y. Chan Wing-Shan Lee Wenlei Peng John Wong Vincent W.S. Wong Henry L.Y. Chan Stephen L. Chan Liona C.Y. Poon
... [+8 authors] ...,
Tak Y. Leung
K.C. Allen Chan
Rossa W.K. Chiu
Y.M. Dennis Lo

First Published August 14, 2020