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Research

Nuclease deficiencies alter plasma cell-free DNA methylation profiles

Diana S.C. Han
Meng Ni
Rebecca W.Y. Chan
Danny K.L. Wong
Linda T. Hiraki
Stefano Volpi Peiyong Jiang
... [+2 authors] ...,
Kathy O. Lui
K.C. Allen Chan
Rossa W.K. Chiu
Y.M. Dennis Lo

First Published September 1, 2021

Method

Detection and characterization of jagged ends of double-stranded DNA in plasma

Peiyong Jiang
Tingting Xie
Spencer C. Ding
Ze Zhou
Suk Hang Cheng
Rebecca W.Y. Chan Wing-Shan Lee Wenlei Peng John Wong Vincent W.S. Wong Henry L.Y. Chan Stephen L. Chan Liona C.Y. Poon
... [+8 authors] ...,
Tak Y. Leung
K.C. Allen Chan
Rossa W.K. Chiu
Y.M. Dennis Lo

First Published August 14, 2020

Method

Orientation-aware plasma cell-free DNA fragmentation analysis in open chromatin regions informs tissue of origin

Kun Sun
Peiyong Jiang
Suk Hang Cheng
Timothy H.T. Cheng
John Wong
Vincent W.S. Wong Simon S.M. Ng Brigette B.Y. Ma Tak Y. Leung Stephen L. Chan Tony S.K. Mok Paul B.S. Lai Henry L.Y. Chan
... [+8 authors] ...,
Hao Sun
K.C. Allen Chan
Rossa W.K. Chiu
Y.M. Dennis Lo

First Published February 26, 2019