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In memoriam

Jim Watson (1928–2025): a genomics visionary

  • First Published July 23, 2026
Perspective

The Topological Regulatory Logic of noncoding RNA–mediated gene expression

  • First Published June 17, 2026
In memoriam

C. Thomas Caskey (1938–2022)

  • First Published February 17, 2022
In memoriam

Deborah A. Nickerson (1954 –2021)

  • First Published January 24, 2022
Research

Bos taurus reveals pervasiveness of X–Y arms races in mammalian lineages" > Sequence analysis in Bos taurus reveals pervasiveness of X–Y arms races in mammalian lineages

  • First Published November 18, 2020
Resource

A limited set of transcriptional programs define major cell types

  • First Published July 29, 2020
Resource

Dynamics of microRNA expression during mouse prenatal development

  • First Published October 23, 2019
Research

Macaca mulatta) based on whole-genome sequences" > The population genomics of rhesus macaques (Macaca mulatta) based on whole-genome sequences

  • First Published October 17, 2016
Research

Postmortem genetic screening for the identification, verification, and reporting of genetic variants contributing to the sudden death of the young

  • First Published July 19, 2016
Insight/Outlook

The ethics of conducting molecular autopsies in cases of sudden death in the young

  • First Published July 13, 2016
Research

Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replication

  • First Published September 16, 2014
Resource

D. melanogaster modENCODE transcriptome annotation" > Comparative validation of the D. melanogaster modENCODE transcriptome annotation

  • First Published July 1, 2014
Resource

Drosophila melanogaster Genetic Reference Panel lines" > Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines

  • First Published April 8, 2014
Research

De novo DNA demethylation and noncoding transcription define active intergenic regulatory elements

  • First Published June 28, 2013
Method

An integrative variant analysis pipeline for accurate genotype/haplotype inference in population NGS data

  • First Published January 7, 2013
Research

Understanding transcriptional regulation by integrative analysis of transcription factor binding data

  • First Published September 5, 2012
Resource

The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression

  • First Published September 5, 2012
Research

Deep sequencing of subcellular RNA fractions shows splicing to be predominantly co-transcriptional in the human genome but inefficient for lncRNAs

  • First Published September 5, 2012
Method

High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression

  • First Published August 30, 2012
Resource

Strongylocentrotus purpuratus based on transcriptome analysis" > Gene structure in the sea urchin Strongylocentrotus purpuratus based on transcriptome analysis

  • First Published June 18, 2012
Resource

Synthetic spike-in standards for RNA-seq experiments

  • First Published August 4, 2011
Resource

Drosophila cell lines" > The transcriptional diversity of 25 Drosophila cell lines

  • First Published December 22, 2010
Resource

A SNP discovery method to assess variant allele probability from next-generation resequencing data

  • First Published December 17, 2009
Resource

The completion of the Mammalian Gene Collection (MGC)

  • First Published September 18, 2009
LETTER

A sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genome

  • First Published December 3, 2008
LETTER

Mouse let-7 miRNA populations exhibit RNA editing that is constrained in the 5′-seed/ cleavage/anchor regions and stabilize predicted mmu-let-7a:mRNA duplexes

  • First Published July 9, 2008
LETTER

Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets

  • First Published February 7, 2008
LETTER

Whole-genome maps of USF1 and USF2 binding and histone H3 acetylation reveal new aspects of promoter structure and candidate genes for common human disorders

  • First Published January 29, 2008
RESOURCE

28-Way vertebrate alignment and conservation track in the UCSC Genome Browser

  • First Published November 5, 2007
LETTER

Structured RNAs in the ENCODE selected regions of the human genome

  • First Published June 13, 2007
ARTICLE

The DART classification of unannotated transcription within the ENCODE regions: Associating transcription with known and novel loci

  • First Published June 13, 2007
ARTICLE

Prominent use of distal 5′ transcription start sites and discovery of a large number of additional exons in ENCODE regions

  • First Published June 13, 2007
ARTICLE

Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome

  • First Published June 13, 2007
PERSPECTIVE

Origin of phenotypes: Genes and transcripts

  • First Published June 13, 2007
COMMENTARY

Community annotation: Procedures, protocols, and supporting tools

  • First Published October 25, 2006
LETTER

Phylogenomic analysis reveals bees and wasps (Hymenoptera) at the base of the radiation of Holometabolous insects

  • First Published October 25, 2006
ARTICLE

Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes

  • First Published July 15, 2005
Methods

Examples of the complex architecture of the human transcriptome revealed by RACE and high-density tiling arrays

  • First Published July 5, 2005
Methods

Highly multiplexed molecular inversion probe genotyping: Over 10,000 targeted SNPs genotyped in a single tube assay

  • First Published February 1, 2005
Methods

Pooled genomic indexing of rhesus macaque

  • First Published February 1, 2005
ARTICLE

Drosophila pseudoobscura: Chromosomal, gene, and cis-element evolution" > Comparative genome sequencing of Drosophila pseudoobscura: Chromosomal, gene, and cis-element evolution

  • First Published January 3, 2005
RESOURCE

The Atlas Genome Assembly System

  • First Published April 1, 2004
LETTER

Genomic Analysis of the Nuclear Receptor Family: New Insights Into Structure, Regulation, and Evolution From the Rat Genome

  • First Published April 1, 2004
Methods

Dynamic Building of a BAC Clone Tiling Path for the Rat Genome Sequencing Project

  • First Published April 1, 2004
Methods

Identification of Rat Genes by TWINSCAN Gene Prediction, RT–PCR, and Direct Sequencing

  • First Published April 1, 2004
ARTICLE

Novel RNAs Identified From an In-Depth Analysis of the Transcriptome of Human Chromosomes 21 and 22

  • First Published March 1, 2004
LETTER

Comparing Vertebrate Whole-Genome Shotgun Reads to the Human Genome

  • First Published November 1, 2001
PERSPECTIVE

A Clone-Array Pooled Shotgun Strategy for Sequencing Large Genomes

  • First Published October 1, 2001
METHODS

Flexible Use of High-Density Oligonucleotide Arrays for Single-Nucleotide Polymorphism Discovery and Validation

  • First Published July 12, 2001
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