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A general calculus of fitness landscapes finds genes under selection in cancers

  • Teng-Kuei Hsu
  • Jennifer Asmussen
  • Amanda Koire
  • Byung-Kwon Choi
  • Mayur A. Gadhikar
  • Eunna Huh Chih-Hsu Lin Daniel M. Konecki Young Won Kim Curtis R. Pickering Marek Kimmel Lawrence A. Donehower
  • ... [+7 authors] ...,
  • Mitchell J. Frederick
  • Jeffrey N. Myers
  • Panagiotis Katsonis
  • Olivier Lichtarge
  • First Published March 17, 2022
Method

A formal perturbation equation between genotype and phenotype determines the Evolutionary Action of protein-coding variations on fitness

  • Panagiotis Katsonis
  • Olivier Lichtarge
  • First Published September 12, 2014
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