Your search for returned 45 results

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Method

Highly accurate assembly polishing with DeepPolisher

  • First Published May 19, 2025
Research

cis-regulatory variation modifies the penetrance of pathogenic SHROOM3 variants in craniofacial microsomia" > Common cis-regulatory variation modifies the penetrance of pathogenic SHROOM3 variants in craniofacial microsomia

  • First Published April 15, 2025
Method

Integration of transcriptomics and long-read genomics prioritizes structural variants in rare disease

  • First Published March 20, 2025
Perspective

Unraveling the hidden complexity of cancer through long-read sequencing

  • First Published March 20, 2025
Review

k-mer approaches for biodiversity genomics" > k-mer approaches for biodiversity genomics

  • First Published January 31, 2025
Method

Gapless assembly of complete human and plant chromosomes using only nanopore sequencing

  • First Published November 6, 2024
Resource

High-coverage nanopore sequencing of samples from the 1000 Genomes Project to build a comprehensive catalog of human genetic variation

  • First Published October 2, 2024
Research

Differences in activity and stability drive transposable element variation in tropical and temperate maize

  • First Published September 9, 2024
Resource

Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes

  • First Published July 1, 2024
Perspective

Diversifying the genomic data science research community

  • First Published July 20, 2022
Perspective

Short arms of human acrocentric chromosomes and the completion of the human genome sequence

  • First Published March 31, 2022
In memoriam

Haig H. Kazazian, Jr. (1937–2022)

  • First Published March 21, 2022
Research

The genomic basis of evolutionary differentiation among honey bees

  • First Published May 4, 2021
Method

Optimized sample selection for cost-efficient long-read population sequencing

  • First Published April 2, 2021
Research

Comprehensive analysis of structural variants in breast cancer genomes using single-molecule sequencing

  • First Published September 4, 2020
Research

Complex rearrangements and oncogene amplifications revealed by long-read DNA and RNA sequencing of a breast cancer cell line

  • First Published June 28, 2018
Research

Slightly deleterious genomic variants and transcriptome perturbations in Down syndrome embryonic selection

  • First Published December 13, 2017
Research

The evolution of inflorescence diversity in the nightshades and heterochrony during meristem maturation

  • First Published November 7, 2016
Research

APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replication

  • First Published January 11, 2016
Method

Oxford Nanopore sequencing, hybrid error correction, and de novo assembly of a eukaryotic genome

  • First Published October 7, 2015
Perspective

Biological data sciences in genome research

  • First Published October 1, 2015
Research

Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders

  • First Published April 27, 2015
Resource

Simultaneous identification and prioritization of variants in familial, de novo, and somatic genetic disorders with VariantMaster

  • First Published January 3, 2014
Research

The complex SNP and CNV genetic architecture of the increased risk of congenital heart defects in Down syndrome

  • First Published June 19, 2013
Resource

Cell-type, allelic, and genetic signatures in the human pancreatic beta cell transcriptome

  • First Published May 28, 2013
Resource

GAGE: A critical evaluation of genome assemblies and assembly algorithms

  • First Published December 6, 2011
Resource

Assemblathon 1: A competitive assessment of de novo short read assembly methods

  • First Published September 16, 2011
Research

DNA methylation profiles of human active and inactive X chromosomes

  • First Published August 23, 2011
Research

cis- and trans-regulatory variation modulating microRNA expression levels in human fibroblasts" > Identification of cis- and trans-regulatory variation modulating microRNA expression levels in human fibroblasts

  • First Published December 8, 2010
Method

Methylation profiling in individuals with uniparental disomy identifies novel differentially methylated regions on chromosome 15

  • First Published July 14, 2010
Perspective

Assembly of large genomes using second-generation sequencing

  • First Published May 27, 2010
Methods

Transcriptional and post-transcriptional profile of human chromosome 21

  • First Published July 6, 2009
RESOURCE

Islands of euchromatin-like sequence and expressed polymorphic sequences within the short arm of human chromosome 21

  • First Published September 25, 2007
ARTICLE

Prominent use of distal 5′ transcription start sites and discovery of a large number of additional exons in ENCODE regions

  • First Published June 13, 2007
ARTICLE

Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome

  • First Published June 13, 2007
LETTER

Pseudogenes in the ENCODE regions: Consensus annotation, analysis of transcription, and evolution

  • First Published June 13, 2007
LETTER

Structured RNAs in the ENCODE selected regions of the human genome

  • First Published June 13, 2007
LETTER

Tandem chimerism as a means to increase protein complexity in the human genome

  • First Published December 12, 2005
LETTER

Gene Expression From the Aneuploid Chromosome in a Trisomy Mouse Model of Down Syndrome

  • First Published July 1, 2004
LETTER

Comparison of Human Chromosome 21 Conserved Nongenic Sequences (CNGs) With the Mouse and Dog Genomes Shows That Their Selective Constraint Is Independent of Their Genic Environment

  • First Published April 12, 2004
RESOURCE

A cSNP Map and Database for Human Chromosome 21

  • First Published January 18, 2001
LETTER

The Mouse Brain Transcriptome by SAGE: Differences in Gene Expression between P30 Brains of the Partial Trisomy 16 Mouse Model of Down Syndrome (Ts65Dn) and Normals

  • First Published December 1, 2000
ARTICLE

Patterns of Meiotic Recombination on the Long Arm of Human Chromosome 21

  • First Published September 1, 2000
LETTER

A High-Resolution Physical Map of Human Chromosome 21p Using Yeast Artificial Chromosomes

  • First Published November 1, 1999
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