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Research

Rearrangements of viral and human genomes at human papillomavirus integration events and their allele-specific impacts on cancer genome regulation

  • First Published December 5, 2024
Research

High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma

  • First Published June 27, 2019
Research

PML protein organizes heterochromatin domains where it regulates histone H3.3 deposition by ATRX/DAXX

  • First Published March 24, 2017
Method

TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data

  • First Published July 24, 2014
Research

The PML-associated protein DEK regulates the balance of H3.3 loading on chromatin and is important for telomere integrity

  • First Published July 21, 2014
Method

Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm

  • First Published June 26, 2013
Method

Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods

  • First Published June 26, 2013
Research

DAXX-dependent supply of soluble (H3.3–H4) dimers to PML bodies pending deposition into chromatin

  • First Published December 5, 2012
Method

Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer

  • First Published May 25, 2012
Research

Extensive relationship between antisense transcription and alternative splicing in the human genome

  • First Published June 30, 2011
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