Research
Rearrangements of viral and human genomes at human papillomavirus integration events and their allele-specific impacts on cancer genome regulation
- First Published December 5, 2024
Perspective
Short arms of human acrocentric chromosomes and the completion of the human genome sequence
- First Published March 31, 2022
Research
High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma
- First Published June 27, 2019
Research
Slightly deleterious genomic variants and transcriptome perturbations in Down syndrome embryonic selection
- First Published December 13, 2017
Research
APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replication
- First Published January 11, 2016
Research
Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders
- First Published April 27, 2015
Method
TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data
- First Published July 24, 2014
Resource
Simultaneous identification and prioritization of variants in familial, de novo, and somatic genetic disorders with VariantMaster
- First Published January 3, 2014
Method
Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm
- First Published June 26, 2013
Method
Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods
- First Published June 26, 2013
Research
The complex SNP and CNV genetic architecture of the increased risk of congenital heart defects in Down syndrome
- First Published June 19, 2013
Resource
Cell-type, allelic, and genetic signatures in the human pancreatic beta cell transcriptome
- First Published May 28, 2013
Research
DNA methylation profiles of human active and inactive X chromosomes
- First Published August 23, 2011
Research
Extensive relationship between antisense transcription and alternative splicing in the human genome
- First Published June 30, 2011
Method
Methylation profiling in individuals with uniparental disomy identifies novel differentially methylated regions on chromosome 15
- First Published July 14, 2010
Research
Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver
- First Published June 15, 2010
Methods
Transcriptional and post-transcriptional profile of human chromosome 21
- First Published July 6, 2009
Methods
Next-generation tag sequencing for cancer gene expression profiling
- First Published June 18, 2009
Resource
C. elegans" > Massively parallel sequencing of the polyadenylated transcriptome of C. elegans
- First Published January 30, 2009
LETTER
In-depth characterization of the microRNA transcriptome in a leukemia progression model
- First Published October 10, 2008
LETTER
Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding
- First Published September 11, 2008
Methods
Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells
- First Published February 19, 2008
RESOURCE
Islands of euchromatin-like sequence and expressed polymorphic sequences within the short arm of human chromosome 21
- First Published September 25, 2007
LETTER
Caenorhabditis elegans operons" > Identification and analysis of internal promoters in Caenorhabditis elegans operons
- First Published August 21, 2007
ARTICLE
Prominent use of distal 5′ transcription start sites and discovery of a large number of additional exons in ENCODE regions
- First Published June 13, 2007
ARTICLE
Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome
- First Published June 13, 2007
LETTER
Pseudogenes in the ENCODE regions: Consensus annotation, analysis of transcription, and evolution
- First Published June 13, 2007
LETTER
Structured RNAs in the ENCODE selected regions of the human genome
- First Published June 13, 2007
Methods
Large-scale production of SAGE libraries from microdissected tissues, flow-sorted cells, and cell lines
- First Published November 29, 2006
LETTER
Identification by full-coverage array CGH of human DNA copy number increases relative to chimpanzee and gorilla
- First Published December 19, 2005
LETTER
Tandem chimerism as a means to increase protein complexity in the human genome
- First Published December 12, 2005
Methods
Simple, robust methods for high-throughput nanoliter-scale DNA sequencing
- First Published September 16, 2005
Methods
Systematic Recovery and Analysis of Full-ORF Human cDNA Clones
- First Published October 15, 2004
LETTER
Gene Expression From the Aneuploid Chromosome in a Trisomy Mouse Model of Down Syndrome
- First Published July 1, 2004
RESOURCE
Development and Application of a Salmonid EST Database and cDNA Microarray: Data Mining and Interspecific Hybridization Characteristics
- First Published February 12, 2004
RESOURCE
Internet Contig Explorer (iCE)—A Tool for Visualizing Clone Fingerprint Maps
- First Published June 1, 2003
RESOURCE
Cryptococcus neoformans " > Physical Maps for Genome Analysis of Serotype A and D Strains of the Fungal Pathogen Cryptococcus neoformans
- First Published August 21, 2002
RESOURCE
An Oligonucleotide Fingerprint Normalized and Expressed Sequence Tag Characterized Zebrafish cDNA Library
- First Published August 16, 2001
ARTICLE
Caenorhabditis elegans " > Changes in Gene Expression Associated with Developmental Arrest and Longevity in Caenorhabditis elegans
- First Published July 12, 2001
METHODS
Theories and Applications for Sequencing Randomly Selected Clones
- First Published January 18, 2001
ARTICLE
Patterns of Meiotic Recombination on the Long Arm of Human Chromosome 21
- First Published September 1, 2000
LETTER
Identifying Potential Tumor Markers and Antigens by Database Mining and Rapid Expression Screening
- First Published September 1, 2000
LETTER
A High-Resolution Physical Map of Human Chromosome 21p Using Yeast Artificial Chromosomes
- First Published November 1, 1999
