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Research

Rearrangements of viral and human genomes at human papillomavirus integration events and their allele-specific impacts on cancer genome regulation

  • First Published December 5, 2024
Research

Bos taurus reveals pervasiveness of X–Y arms races in mammalian lineages" > Sequence analysis in Bos taurus reveals pervasiveness of X–Y arms races in mammalian lineages

  • First Published November 18, 2020
Research

High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma

  • First Published June 27, 2019
Corrigendum

Corrigendum: Discovery and genotyping of structural variation from long-read haploid genome sequence data

  • First Published January 2, 2018
Corrigendum

Corrigendum: The evolution of African great ape subtelomeric heterochromatin and the fusion of human chromosome 2

  • First Published September 1, 2017
Resource

Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly

  • First Published April 10, 2017
Research

Discovery and genotyping of structural variation from long-read haploid genome sequence data

  • First Published November 28, 2016
Research

Interchromosomal core duplicons drive both evolutionary instability and disease susceptibility of the Chromosome 8p23.1 region

  • First Published October 7, 2016
Research

Pangolin genomes and the evolution of mammalian scales and immunity

  • First Published August 10, 2016
Method

INTEGRATE: gene fusion discovery using whole genome and transcriptome data

  • First Published November 10, 2015
Resource

Single haplotype assembly of the human genome from a hydatidiform mole

  • First Published November 4, 2014
Method

TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data

  • First Published July 24, 2014
Resource

Subtelomeric CTCF and cohesin binding site organization using improved subtelomere assemblies and a novel annotation pipeline

  • First Published March 27, 2014
Method

Reconstructing complex regions of genomes using long-read sequencing technology

  • First Published January 13, 2014
Method

Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm

  • First Published June 26, 2013
Method

Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods

  • First Published June 26, 2013
Resource

MuSiC: Identifying mutational significance in cancer genomes

  • First Published July 3, 2012
Method

Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer

  • First Published May 25, 2012
Research

The evolution of African great ape subtelomeric heterochromatin and the fusion of human chromosome 2

  • First Published March 14, 2012
Research

Extensive relationship between antisense transcription and alternative splicing in the human genome

  • First Published June 30, 2011
Research

Gorilla genome structural variation reveals evolutionary parallelisms with chimpanzee

  • First Published June 17, 2011
Research

Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence" > Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence

  • First Published December 22, 2010
Research

Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver

  • First Published June 15, 2010
Resource

The completion of the Mammalian Gene Collection (MGC)

  • First Published September 18, 2009
Methods

Next-generation tag sequencing for cancer gene expression profiling

  • First Published June 18, 2009
Resource

Circos: An information aesthetic for comparative genomics

  • First Published June 18, 2009
LETTER

Sequencing human–gibbon breakpoints of synteny reveals mosaic new insertions at rearrangement sites

  • First Published November 24, 2008
LETTER

In-depth characterization of the microRNA transcriptome in a leukemia progression model

  • First Published October 10, 2008
RESOURCE

Haplotype sorting using human fosmid clone end-sequence pairs

  • First Published October 3, 2008
LETTER

Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding

  • First Published September 11, 2008
Methods

Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells

  • First Published February 19, 2008
LETTER

Caenorhabditis elegans operons" > Identification and analysis of internal promoters in Caenorhabditis elegans operons

  • First Published August 21, 2007
ARTICLE

Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome

  • First Published June 13, 2007
RESOURCE

PolyScan: An automatic indel and SNP detection approach to the analysis of human resequencing data

  • First Published April 6, 2007
RESOURCE

Molecular refinement of gibbon genome rearrangements

  • First Published December 21, 2006
Methods

Large-scale production of SAGE libraries from microdissected tissues, flow-sorted cells, and cell lines

  • First Published November 29, 2006
Methods

Physical map-assisted whole-genome shotgun sequence assemblies

  • First Published June 1, 2006
RESOURCE

Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling" > Sequencing and analysis of 10,967 full-length cDNA clones from Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling

  • First Published May 3, 2006
LETTER

Identification by full-coverage array CGH of human DNA copy number increases relative to chimpanzee and gorilla

  • First Published December 19, 2005
Methods

Simple, robust methods for high-throughput nanoliter-scale DNA sequencing

  • First Published September 16, 2005
ARTICLE

Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes

  • First Published July 15, 2005
LETTER

Punctuated duplication seeding events during the evolution of human chromosome 2p11

  • First Published June 17, 2005
ARTICLE

C. elegans daf-2 mutants using serial analysis of gene expression" > Analysis of long-lived C. elegans daf-2 mutants using serial analysis of gene expression

  • First Published April 18, 2005
RESOURCE

EAnnot: A genome annotation tool using experimental evidence

  • First Published December 1, 2004
Methods

Systematic Recovery and Analysis of Full-ORF Human cDNA Clones

  • First Published October 15, 2004
LETTER

Analysis of Human mRNAs With the Reference Genome Sequence Reveals Potential Errors, Polymorphisms, and RNA Editing

  • First Published October 15, 2004
Chicken Special/Letters

The repetitive landscape of the chicken genome

  • First Published July 15, 2004
RESOURCE

Development and Application of a Salmonid EST Database and cDNA Microarray: Data Mining and Interspecific Hybridization Characteristics

  • First Published February 12, 2004
RESOURCE

Internet Contig Explorer (iCE)—A Tool for Visualizing Clone Fingerprint Maps

  • First Published June 1, 2003
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