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Research

Rearrangements of viral and human genomes at human papillomavirus integration events and their allele-specific impacts on cancer genome regulation

  • First Published December 5, 2024
In memoriam

C. Thomas Caskey (1938–2022)

  • First Published February 17, 2022
In memoriam

Deborah A. Nickerson (1954 –2021)

  • First Published January 24, 2022
Research

Bos taurus reveals pervasiveness of X–Y arms races in mammalian lineages" > Sequence analysis in Bos taurus reveals pervasiveness of X–Y arms races in mammalian lineages

  • First Published November 18, 2020
Research

High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma

  • First Published June 27, 2019
Research

Macaca mulatta) based on whole-genome sequences" > The population genomics of rhesus macaques (Macaca mulatta) based on whole-genome sequences

  • First Published October 17, 2016
Research

Postmortem genetic screening for the identification, verification, and reporting of genetic variants contributing to the sudden death of the young

  • First Published July 19, 2016
Insight/Outlook

The ethics of conducting molecular autopsies in cases of sudden death in the young

  • First Published July 13, 2016
Research

Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replication

  • First Published September 16, 2014
Method

TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data

  • First Published July 24, 2014
Resource

D. melanogaster modENCODE transcriptome annotation" > Comparative validation of the D. melanogaster modENCODE transcriptome annotation

  • First Published July 1, 2014
Resource

Drosophila melanogaster Genetic Reference Panel lines" > Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines

  • First Published April 8, 2014
Method

Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm

  • First Published June 26, 2013
Method

Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods

  • First Published June 26, 2013
Method

An integrative variant analysis pipeline for accurate genotype/haplotype inference in population NGS data

  • First Published January 7, 2013
Resource

Strongylocentrotus purpuratus based on transcriptome analysis" > Gene structure in the sea urchin Strongylocentrotus purpuratus based on transcriptome analysis

  • First Published June 18, 2012
Method

Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer

  • First Published May 25, 2012
Research

Extensive relationship between antisense transcription and alternative splicing in the human genome

  • First Published June 30, 2011
Research

Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence" > Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence

  • First Published December 22, 2010
Research

Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver

  • First Published June 15, 2010
Resource

A SNP discovery method to assess variant allele probability from next-generation resequencing data

  • First Published December 17, 2009
Resource

The completion of the Mammalian Gene Collection (MGC)

  • First Published September 18, 2009
Methods

Next-generation tag sequencing for cancer gene expression profiling

  • First Published June 18, 2009
Resource

Circos: An information aesthetic for comparative genomics

  • First Published June 18, 2009
Resource

C. elegans" > Massively parallel sequencing of the polyadenylated transcriptome of C. elegans

  • First Published January 30, 2009
LETTER

A sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genome

  • First Published December 3, 2008
LETTER

In-depth characterization of the microRNA transcriptome in a leukemia progression model

  • First Published October 10, 2008
LETTER

Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding

  • First Published September 11, 2008
LETTER

Mouse let-7 miRNA populations exhibit RNA editing that is constrained in the 5′-seed/ cleavage/anchor regions and stabilize predicted mmu-let-7a:mRNA duplexes

  • First Published July 9, 2008
Methods

Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells

  • First Published February 19, 2008
RESOURCE

28-Way vertebrate alignment and conservation track in the UCSC Genome Browser

  • First Published November 5, 2007
LETTER

Caenorhabditis elegans operons" > Identification and analysis of internal promoters in Caenorhabditis elegans operons

  • First Published August 21, 2007
ARTICLE

Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome

  • First Published June 13, 2007
Methods

Large-scale production of SAGE libraries from microdissected tissues, flow-sorted cells, and cell lines

  • First Published November 29, 2006
COMMENTARY

Community annotation: Procedures, protocols, and supporting tools

  • First Published October 25, 2006
LETTER

Phylogenomic analysis reveals bees and wasps (Hymenoptera) at the base of the radiation of Holometabolous insects

  • First Published October 25, 2006
Methods

Physical map-assisted whole-genome shotgun sequence assemblies

  • First Published June 1, 2006
RESOURCE

Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling" > Sequencing and analysis of 10,967 full-length cDNA clones from Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling

  • First Published May 3, 2006
LETTER

Identification by full-coverage array CGH of human DNA copy number increases relative to chimpanzee and gorilla

  • First Published December 19, 2005
Methods

Simple, robust methods for high-throughput nanoliter-scale DNA sequencing

  • First Published September 16, 2005
ARTICLE

Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes

  • First Published July 15, 2005
ARTICLE

C. elegans daf-2 mutants using serial analysis of gene expression" > Analysis of long-lived C. elegans daf-2 mutants using serial analysis of gene expression

  • First Published April 18, 2005
Methods

Highly multiplexed molecular inversion probe genotyping: Over 10,000 targeted SNPs genotyped in a single tube assay

  • First Published February 1, 2005
Methods

Pooled genomic indexing of rhesus macaque

  • First Published February 1, 2005
ARTICLE

Drosophila pseudoobscura: Chromosomal, gene, and cis-element evolution" > Comparative genome sequencing of Drosophila pseudoobscura: Chromosomal, gene, and cis-element evolution

  • First Published January 3, 2005
Methods

Systematic Recovery and Analysis of Full-ORF Human cDNA Clones

  • First Published October 15, 2004
RESOURCE

The Atlas Genome Assembly System

  • First Published April 1, 2004
LETTER

Genomic Analysis of the Nuclear Receptor Family: New Insights Into Structure, Regulation, and Evolution From the Rat Genome

  • First Published April 1, 2004
Methods

Identification of Rat Genes by TWINSCAN Gene Prediction, RT–PCR, and Direct Sequencing

  • First Published April 1, 2004
Methods

Dynamic Building of a BAC Clone Tiling Path for the Rat Genome Sequencing Project

  • First Published April 1, 2004
RESOURCE

Development and Application of a Salmonid EST Database and cDNA Microarray: Data Mining and Interspecific Hybridization Characteristics

  • First Published February 12, 2004
RESOURCE

Internet Contig Explorer (iCE)—A Tool for Visualizing Clone Fingerprint Maps

  • First Published June 1, 2003
Methods

Assessment of SAGE in Transcript Identification

  • First Published May 12, 2003
METHODS

Software for Automated Analysis of DNA Fingerprinting Gels

  • First Published May 1, 2003
RESOURCE

Cryptococcus neoformans " > Physical Maps for Genome Analysis of Serotype A and D Strains of the Fungal Pathogen Cryptococcus neoformans

  • First Published August 21, 2002
LETTER

Comparing Vertebrate Whole-Genome Shotgun Reads to the Human Genome

  • First Published November 1, 2001
PERSPECTIVE

A Clone-Array Pooled Shotgun Strategy for Sequencing Large Genomes

  • First Published October 1, 2001
RESOURCE

An Oligonucleotide Fingerprint Normalized and Expressed Sequence Tag Characterized Zebrafish cDNA Library

  • First Published August 16, 2001
ARTICLE

Caenorhabditis elegans " > Changes in Gene Expression Associated with Developmental Arrest and Longevity in Caenorhabditis elegans

  • First Published July 12, 2001
METHODS

Theories and Applications for Sequencing Randomly Selected Clones

  • First Published January 18, 2001
LETTER

Identifying Potential Tumor Markers and Antigens by Database Mining and Rapid Expression Screening

  • First Published September 1, 2000
LETTER

CMT2D Locus: Refined Genetic Position and Construction of a Bacterial Clone-Based Physical Map" > The CMT2D Locus: Refined Genetic Position and Construction of a Bacterial Clone-Based Physical Map

  • First Published June 1, 1999
GENOME METHODS

Analysis of the Quality and Utility of Random Shotgun Sequencing at Low Redundancies

  • First Published October 1, 1998
RESEARCH

Comparative Sequence Analysis of a Gene-Rich Cluster at Human Chromosome 12p13 and its Syntenic Region in Mouse Chromosome 6

  • First Published January 1, 1998
LETTER

High Throughput Fingerprint Analysis of Large-Insert Clones

  • First Published November 1, 1997
LETTER

SNRPN Promoter: In Vitro Methylation Abolishes Promoter Activity" > Sequencing and Functional Analysis of the SNRPN Promoter: In Vitro Methylation Abolishes Promoter Activity

  • First Published June 1, 1997
RESEARCH

Large-Scale Comparative Sequence Analysis of the Human and Murine Bruton’s Tyrosine Kinase Loci Reveals Conserved Regulatory Domains

  • First Published April 1, 1997
LETTER

Large-Scale Concatenation cDNA Sequencing

  • First Published April 1, 1997
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