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Resource

Single-nucleus multiomic profiling of the aging mouse substantia nigra reveals conserved gene alterations linked to Parkinson's disease

Kangli Wang
Weikun Xia
Yingli Gu
Songpeng Zu
Qian Yang
Maria Luisa Amaral Yaozhi Wang
... [+2 authors] ...,
Allen Wang
Xiang-Dong Fu
William C. Mobley
Bing Ren

First Published March 4, 2026

Research

Active retrotransposons help maintain pericentromeric heterochromatin required for faithful cell division

Yajing Hao
Dongpeng Wang
Shuheng Wu
Xiao Li
Changwei Shao
Peng Zhang Jia-Yu Chen
... [+2 authors] ...,
Do-Hwan Lim
Xiang-Dong Fu
Runsheng Chen
Shunmin He

First Published October 15, 2020

Research

Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target

Myungjin Jo
Ah Young Chung
Nozomu Yachie
Minchul Seo
Hyejin Jeon
Youngpyo Nam Yeojin Seo Eunmi Kim Quan Zhong
... [+4 authors] ...,
Marc Vidal
Hae Chul Park
Frederick P. Roth
Kyoungho Suk

First Published June 8, 2017

Method

An extended set of yeast-based functional assays accurately identifies human disease mutations

Song Sun
Fan Yang
Guihong Tan
Michael Costanzo
Rose Oughtred
Jodi Hirschman Chandra L. Theesfeld Pritpal Bansal Nidhi Sahni Song Yi Analyn Yu Tanya Tyagi Cathy Tie David E. Hill Marc Vidal
... [+10 authors] ...,
Brenda J. Andrews
Charles Boone
Kara Dolinski
Frederick P. Roth

First Published March 14, 2016

Resource

C. elegans ORFeome" > Large-scale RACE approach for proactive experimental definition of C. elegans ORFeome

Kourosh Salehi-Ashtiani
Chenwei Lin
Tong Hao
Yun Shen
David Szeto
Xinping Yang Lila Ghamsari HanJoo Lee Changyu Fan Ryan R. Murray Stuart Milstein Nenad Svrzikapa
... [+7 authors] ...,
Michael E. Cusick
Frederick P. Roth
David E. Hill
Marc Vidal

First Published October 2, 2009

Resource

Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network

Gabriel Markson
Christina Kiel
Russell Hyde
Stephanie Brown
Panagoula Charalabous
Anja Bremm Jennifer Semple Jonathan Woodsmith Simon Duley Kourosh Salehi-Ashtiani Marc Vidal
... [+6 authors] ...,
David Komander
Luis Serrano
Paul Lehner
Christopher M. Sanderson

First Published June 23, 2009

Methods

Shifted Transversal Design smart-pooling for high coverage interactome mapping

Xiaofeng Xin
Jean-François Rual
Tomoko Hirozane-Kishikawa
David E. Hill
Marc Vidal
Charles Boone
Nicolas Thierry-Mieg

First Published May 15, 2009

LETTER

Saccharomyces cerevisiae predicted ORFeome" > Revisiting the Saccharomyces cerevisiae predicted ORFeome

Qian-Ru Li
Anne-Ruxandra Carvunis
Haiyuan Yu
Jing-Dong J. Han
Quan Zhong
Nicolas Simonis Stanley Tam Tong Hao Niels J. Klitgord Denis Dupuy Danny Mou Ilan Wapinski
... [+7 authors] ...,
Aviv Regev
David E. Hill
Michael E. Cusick
Marc Vidal

First Published May 23, 2008

RESOURCE

C. elegans ORFeome by cloning TWINSCAN predictions" > Closing in on the C. elegans ORFeome by cloning TWINSCAN predictions

Chaochun Wei
Philippe Lamesch
Manimozhiyan Arumugam
Jennifer Rosenberg
Ping Hu
Marc Vidal
Michael R. Brent

First Published April 1, 2005

LETTER

C. elegans embryo revealed using RNAi of ovary-enriched ORFeome clones" > New genes with roles in the C. elegans embryo revealed using RNAi of ovary-enriched ORFeome clones

Anita G. Fernandez
Kristin C. Gunsalus
Jerry Huang
Ling-Shiang Chuang
Nancy Ying
Hsiao-lan Liang Caroline Tang Aaron J. Schetter Charles Zegar Jean-François Rual
... [+5 authors] ...,
David E. Hill
Valerie Reinke
Marc Vidal
Fabio Piano

First Published February 1, 2005

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