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Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target

Myungjin Jo
Ah Young Chung
Nozomu Yachie
Minchul Seo
Hyejin Jeon
Youngpyo Nam Yeojin Seo Eunmi Kim Quan Zhong
... [+4 authors] ...,
Marc Vidal
Hae Chul Park
Frederick P. Roth
Kyoungho Suk

First Published June 8, 2017

An extended set of yeast-based functional assays accurately identifies human disease mutations

Song Sun
Fan Yang
Guihong Tan
Michael Costanzo
Rose Oughtred
Jodi Hirschman Chandra L. Theesfeld Pritpal Bansal Nidhi Sahni Song Yi Analyn Yu Tanya Tyagi Cathy Tie David E. Hill Marc Vidal
... [+10 authors] ...,
Brenda J. Andrews
Charles Boone
Kara Dolinski
Frederick P. Roth

First Published March 14, 2016

Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution

Hoon Kim
Siyuan Zheng
Seyed S. Amini
Selene M. Virk
Tom Mikkelsen
Daniel J. Brat Jonna Grimsby Carrie Sougnez Florian Muller Jian Hu Andrew E. Sloan Mark L. Cohen Erwin G. Van Meir Lisa Scarpace Peter W. Laird John N. Weinstein Eric S. Lander Stacey Gabriel Gad Getz
... [+14 authors] ...,
Matthew Meyerson
Lynda Chin
Jill S. Barnholtz-Sloan
Roel G.W. Verhaak

First Published February 3, 2015

Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration

Weisheng Wu
Yong Cheng
Cheryl A. Keller
Jason Ernst
Swathi Ashok Kumar
Tejaswini Mishra Christapher Morrissey Christine M. Dorman Kuan-Bei Chen Daniela Drautz Belinda Giardine Yoichiro Shibata Lingyun Song Max Pimkin Gregory E. Crawford Terrence S. Furey Manolis Kellis Webb Miller James Taylor Stephan C. Schuster Yu Zhang
... [+16 authors] ...,
Francesca Chiaromonte
Gerd A. Blobel
Mitchell J. Weiss
Ross C. Hardison

First Published July 27, 2011

Genome-scale analysis of aberrant DNA methylation in colorectal cancer

Toshinori Hinoue
Daniel J. Weisenberger
Christopher P.E. Lange
Hui Shen
Hyang-Min Byun
David Van Den Berg Simeen Malik Fei Pan
... [+3 authors] ...,
Houtan Noushmehr
Cornelis M. van Dijk
Rob A.E.M. Tollenaar
Peter W. Laird

First Published June 9, 2011

Genome-wide identification of conserved regulatory function in diverged sequences

Leila Taher
David M. McGaughey
Samantha Maragh
Ivy Aneas
Seneca L. Bessling
Webb Miller
Marcelo A. Nobrega
Andrew S. McCallion
Ivan Ovcharenko

First Published May 31, 2011

Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer

Andrew E. Teschendorff
Usha Menon
Aleksandra Gentry-Maharaj
Susan J. Ramus
Daniel J. Weisenberger
Hui Shen Mihaela Campan Houtan Noushmehr Christopher G. Bell A. Peter Maxwell David A. Savage Elisabeth Mueller-Holzner Christian Marth Gabrijela Kocjan Simon A. Gayther Allison Jones Stephan Beck
... [+12 authors] ...,
Wolfgang Wagner
Peter W. Laird
Ian J. Jacobs
Martin Widschwendter

First Published March 10, 2010

Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression

Yong Cheng
Weisheng Wu
Swathi Ashok Kumar
Duonan Yu
Wulan Deng
Tamara Tripic David C. King Kuan-Bei Chen Ying Zhang Daniela Drautz Belinda Giardine Stephan C. Schuster Webb Miller Francesca Chiaromonte
... [+9 authors] ...,
Yu Zhang
Gerd A. Blobel
Mitchell J. Weiss
Ross C. Hardison

First Published November 3, 2009

C. elegans ORFeome" > Large-scale RACE approach for proactive experimental definition of C. elegans ORFeome

Kourosh Salehi-Ashtiani
Chenwei Lin
Tong Hao
Yun Shen
David Szeto
Xinping Yang Lila Ghamsari HanJoo Lee Changyu Fan Ryan R. Murray Stuart Milstein Nenad Svrzikapa
... [+7 authors] ...,
Michael E. Cusick
Frederick P. Roth
David E. Hill
Marc Vidal

First Published October 2, 2009

Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network

Gabriel Markson
Christina Kiel
Russell Hyde
Stephanie Brown
Panagoula Charalabous
Anja Bremm Jennifer Semple Jonathan Woodsmith Simon Duley Kourosh Salehi-Ashtiani Marc Vidal
... [+6 authors] ...,
David Komander
Luis Serrano
Paul Lehner
Christopher M. Sanderson

First Published June 23, 2009

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