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Method

CRISPR RNAs trigger innate immune responses in human cells

  • First Published February 22, 2018
Research

Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target

  • First Published June 8, 2017
Method

An extended set of yeast-based functional assays accurately identifies human disease mutations

  • First Published March 14, 2016
Method

Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq

  • First Published January 19, 2016
Method

Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins

  • First Published April 2, 2014
Method

Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases

  • First Published November 19, 2013
Method

Haplotype-based profiling of subtle allelic imbalance with SNP arrays

  • First Published October 1, 2012
Method

Precision genome engineering with programmable DNA-nicking enzymes

  • First Published April 20, 2012
Research

SLCO1B1 variation and methotrexate disposition" > Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition

  • First Published December 6, 2011
Resource

C. elegans ORFeome" > Large-scale RACE approach for proactive experimental definition of C. elegans ORFeome

  • First Published October 2, 2009
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